Hydrogels Constructed from Engineered Proteins

被引：71
作者：
Li, Hongbin [1 ]
Kong, Na [1 ]
Laver, Bryce [1 ]
Liu, Junqiu [2 ]
机构：
[1] Univ British Columbia, Dept Chem, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada
[2] Jilin Univ, Key Lab Supramol Struct & Mat, Changchun 130012, Jilin Province, Peoples R China
来源：
SMALL | 2016年 / 12卷 / 08期
基金：
中国国家自然科学基金;
关键词：
ELASTIN-LIKE POLYPEPTIDE; CROSS-LINKING; FRAGMENT RECONSTITUTION; DRUG-DELIVERY; IN-SITU; MECHANICAL-PROPERTIES; CONFORMATIONAL-CHANGE; DESIGNING MATERIALS; CRYSTAL-STRUCTURE; BLOCK-COPOLYMERS;
D O I：
10.1002/smll.201502429
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Due to their various potential biomedical applications, hydrogels based on engineered proteins have attracted considerable interest. Benefitting from significant progress in recombinant DNA technology and protein engineering/design techniques, the field of protein hydrogels has made amazing progress. The latest progress of hydrogels constructed from engineered recombinant proteins are presented, mainly focused on biorecognition-driven physical hydrogels as well as chemically crosslinked hydrogels. The various bio-recognition based physical crosslinking strategies are discussed, as well as chemical crosslinking chemistries used to engineer protein hydrogels, and protein hydrogels' various biomedical applications. The future perspectives of this fast evolving field of biomaterials are also discussed.
引用
收藏
页码：973 / 987
页数：15
相关论文
共 128 条
[31]   A highly elastic tissue sealant based on photopolymerised gelatin [J].
Elvin, Christopher M. ;
Vuocolo, Tony ;
Brownlee, Alan G. ;
Sando, Lillian ;
Huson, Mickey G. ;
Liyou, Nancy E. ;
Stockwell, Peter R. ;
Lyons, Russell E. ;
Kim, Misook ;
Edwards, Glenn A. ;
Johnson, Graham ;
McFarland, Gail A. ;
Ramshaw, John A. M. ;
Werkmeister, Jerome A. .
BIOMATERIALS, 2010, 31 (32) :8323-8331
[32]   The development of photochemically crosslinked native fibrinogen as a rapidly formed and mechanically strong surgical tissue sealant [J].
Elvin, Christopher M. ;
Brownlee, Alan G. ;
Huson, Mickey G. ;
Tebb, Tracy A. ;
Kim, Misook ;
Lyons, Russell E. ;
Vuocolo, Tony ;
Liyou, Nancy E. ;
Hughes, Timothy C. ;
Ramshaw, John A. M. ;
Werkmeister, Jerome A. .
BIOMATERIALS, 2009, 30 (11) :2059-2065
[33]   Synthesis and properties of crosslinked recombinant pro-resilin [J].
Elvin, CM ;
Carr, AG ;
Huson, MG ;
Maxwell, JM ;
Pearson, RD ;
Vuocolo, T ;
Liyou, NE ;
Wong, DCC ;
Merritt, DJ ;
Dixon, NE .
NATURE, 2005, 437 (7061) :999-1002
[34]   Matrix elasticity directs stem cell lineage specification [J].
Engler, Adam J. ;
Sen, Shamik ;
Sweeney, H. Lee ;
Discher, Dennis E. .
CELL, 2006, 126 (04) :677-689
[35]   Chemistry for the analysis of protein-protein interactions: Rapid and efficient cross-linking triggered by long wavelength light [J].
Fancy, DA ;
Kodadek, T .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (11) :6020-6024
[36]   Forced protein unfolding leads to highly elastic and tough protein hydrogels [J].
Fang, Jie ;
Mehlich, Alexander ;
Koga, Nobuyasu ;
Huang, Jiqing ;
Koga, Rie ;
Gao, Xiaoye ;
Hu, Chunguang ;
Jin, Chi ;
Rief, Matthias ;
Kast, Juergen ;
Baker, David ;
Li, Hongbin .
NATURE COMMUNICATIONS, 2013, 4
[37]   A Facile Way to Tune Mechanical Properties of Artificial Elastomeric Proteins-Based Hydrogels [J].
Fang, Jie ;
Li, Hongbin .
LANGMUIR, 2012, 28 (21) :8260-8265
[38]   Self-assembly of short peptides to form hydrogels: Design of building blocks, physical properties and technological applications [J].
Fichman, Galit ;
Gazit, Ehud .
ACTA BIOMATERIALIA, 2014, 10 (04) :1671-1682
[39]   Predicting specificity in bZIP coiled-coil protein interactions [J].
Fong, JH ;
Keating, AE ;
Singh, M .
GENOME BIOLOGY, 2004, 5 (02)
[40]   Two-component protein-engineered physical hydrogels for cell encapsulation [J].
Foo, Cheryl T. S. Wong Po ;
Lee, Ji Seok ;
Mulyasasmita, Widya ;
Parisi-Amon, Andreina ;
Heilshorn, Sarah C. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (52) :22067-22072
12345678910