Catalytic Generation of Cesium Acetylide by CsF: Synthesis of 1,3-Benzothiazines from Cyclic Sulfenamides

被引：28
作者：
Spitz, Cedric [1 ]
Lohier, Jean-Francois [1 ]
Reboul, Vincent [1 ]
Metzner, Patrick [1 ]
机构：
[1] Univ Caen Basse Normandie, ENSICAEN, Lab Chim Mol & Thio Organ, CNRS, F-14050 Caen, France
来源：
ORGANIC LETTERS | 2009年 / 11卷 / 13期
关键词：
HIGHLY ENANTIOSELECTIVE SYNTHESIS; GAMMA-HYDROXY-ALPHA; BETA-ACETYLENIC ESTERS; TERMINAL ALKYNES; ALDEHYDES; ALKYNYLATION; HYDROXIDE; KETONES; ACETYLENES; ADDITIONS; BASE;
D O I：
10.1021/ol9009333
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient synthesis of enantiopure 1,3-benzothiazines has been achieved by reaction of cyclic sulfenamides and alkylpropiolate or tosylacetylene catalyzed by cesium fluoride.
引用
收藏
页码：2776 / 2779
页数：4
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