One-Pot Synthesis of Polysubstituted Spirofluorene-Indene via Ru(II)-Catalyzed [3+2] Annulation and Intramolecular Friedel-Crafts Cyclization

被引：16

作者：

Zhu, Yu-Qin ^{[1
]}

Dong, Lin ^{[1
]}

机构：

[1] Sichuan Univ, West China Sch Pharm, Educ Minist, Key Lab Drug Targeting & Drug Delivery Syst, Chengdu 610041, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 80卷 / 20期

关键词：

C-H ACTIVATION; AMBIPOLAR CARRIER TRANSPORT; DISCOTIC LIQUID-CRYSTALS; LIGHT-EMITTING MATERIALS; BOND ACTIVATION; HYDROCARBON HOST; ORTHO-LINKAGE; ARYL KETONES; ALKYNES; DERIVATIVES;

D O I：

10.1021/acs.joc.5b01517

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ru(II)-catalyzed one-pot synthesis of polysubstituted spirofluorene-indenes via [3 + 2] annulation and then intramolecular Friedel Crafts alkylation has been achieved. The simple method provides a broad scope of aryl ketones and internal alkynes, achieving PAHs skeletons in moderate to good yields.

引用

页码：9973 / 9979

页数：7

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