Estimation of bulk optical properties of turbid media from hyperspectral scatter imaging measurements: metamodeling approach

被引：11

作者：

Aernouts, Ben ^{[1
]}

Erkinbaev, Chyngyz ^{[1
]}

Watte, Rodrigo ^{[1
]}

Van Beers, Robbe ^{[1
]}

Nghia Nguyen Do Trong ^{[1
]}

Nicolai, Bart ^{[1
]}

Saeys, Wouter ^{[1
]}

机构：

[1] Katholieke Univ Leuven, MeBioS, Dept Biosyst, B-3001 Leuven, Belgium

来源：

OPTICS EXPRESS | 2015年 / 23卷 / 20期

关键词：

MONTE-CARLO-SIMULATION; DIFFUSE-REFLECTANCE MEASUREMENTS; INTEGRATING SPHERE MEASUREMENTS; NONINVASIVE DETERMINATION; ENGINEERING DESIGN; BIOLOGICAL TISSUE; LIGHT TRANSPORT; ABSORPTION; SPECTROSCOPY; COEFFICIENTS;

D O I：

10.1364/OE.23.026049

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

In many research areas and application domains, the bulk optical properties of biological materials are of great interest. Unfortunately, these properties cannot be obtained easily for complex turbid media. In this study, a metamodeling approach has been proposed and applied for the fast and accurate estimation of the bulk optical properties from contactless and non-destructive hyperspectral scatter imaging (HSI) measurements. A set of liquid optical phantoms, based on intralipid, methylene blue and water, were prepared and the Vis/NIR bulk optical properties were characterized with a double integrating sphere and unscattered transmittance setup. Accordingly, the phantoms were measured with the HSI technique and metamodels were constructed, relating the Vis/NIR reflectance images to the reference bulk optical properties of the samples. The independent inverse validation showed good prediction performance for the absorption coefficient and the reduced scattering coefficient, with 2 R-1(2), values of 0.980 and 0.998, and RMSEP values of 0.032 cm(-1) and 0.197 cm(-1). respectively. The results clearly support the potential of this approach for fast and accurate estimation of the bulk optical properties of turbid media from contactless HSI measurements. (C) 2015 Optical Society of America

引用

页码：26049 / 26063

页数：15

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