共 73 条
The current state of adverse event reporting in hemophilia
被引:2
作者:

van Vulpen, Lize F. D.
论文数: 0 引用数: 0
h-index: 0
机构:
Royal Hallamshire Hosp, Sheffield Haemophilia & Thrombosis Ctr, Glossop Rd, Sheffield S10 2JF, S Yorkshire, England
Univ Med Ctr Utrecht, Van Creveldklin, Utrecht, Netherlands Royal Hallamshire Hosp, Sheffield Haemophilia & Thrombosis Ctr, Glossop Rd, Sheffield S10 2JF, S Yorkshire, England

Saccullo, Giorgia
论文数: 0 引用数: 0
h-index: 0
机构:
Royal Hallamshire Hosp, Sheffield Haemophilia & Thrombosis Ctr, Glossop Rd, Sheffield S10 2JF, S Yorkshire, England Royal Hallamshire Hosp, Sheffield Haemophilia & Thrombosis Ctr, Glossop Rd, Sheffield S10 2JF, S Yorkshire, England

Iorio, Alfonso
论文数: 0 引用数: 0
h-index: 0
机构:
McMaster Univ, Dept Clin Epidemiol & Biostat, Hamilton, ON, Canada Royal Hallamshire Hosp, Sheffield Haemophilia & Thrombosis Ctr, Glossop Rd, Sheffield S10 2JF, S Yorkshire, England

论文数: 引用数:
h-index:
机构:
机构:
[1] Royal Hallamshire Hosp, Sheffield Haemophilia & Thrombosis Ctr, Glossop Rd, Sheffield S10 2JF, S Yorkshire, England
[2] Univ Med Ctr Utrecht, Van Creveldklin, Utrecht, Netherlands
[3] McMaster Univ, Dept Clin Epidemiol & Biostat, Hamilton, ON, Canada
[4] Univ Sheffield, Dept Infect Immun & Cardiovasc Dis, Sheffield, S Yorkshire, England
关键词:
Bleeding disorders;
haemophilia;
safety;
surveillance;
concentrate;
RECOMBINANT FACTOR-VIII;
HEPATITIS-C VIRUS;
INHIBITOR DEVELOPMENT;
SAFETY SURVEILLANCE;
BLEEDING DISORDERS;
UNITED-KINGDOM;
A PATIENTS;
CHILDREN;
LIFE;
PRODUCTS;
D O I:
10.1080/17474086.2017.1272410
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Introduction: Replacement of the missing clotting factor is the mainstay of hemophilia treatment. Whilst historically many hemophilia patients were infected with blood-borne viruses transmitted via plasma-derived products, nowadays the formation of alloantibodies against the missing clotting factor is the main adverse event of treatment.Areas covered: This paper provides an overview of the current national and international adverse event reporting systems, what these surveillance schemes taught us about side effects of the products presently in use, and elaborates on how to adapt these systems to the challenges we face with the changing treatment landscape.Expert commentary: Treatment of inherited bleeding disorders was accompanied by severe complications in the past, resulting in major morbidity and mortality. Current products are much safer, but still require monitoring via efficient safety surveillance systems. Adverse events are reported in national and international systems. With many new products entering the market, as well as non-factor replacement therapies, new safety issues may arise. It is important to identify potential adverse events early by making surveillance systems suitable to pick up unknown or unexpected effects, and to recognize and communicate patterns of adverse events rapidly.
引用
收藏
页码:161 / 168
页数:8
相关论文
共 73 条
- [11] Safety and efficacy of recombinant activated factor VII in nonhemophilia children with severe or life-threatening bleeding: a report from the SeveNBleeP registry[J]. BLOOD COAGULATION & FIBRINOLYSIS, 2014, 25 (04) : 326 - 332Blatny, Jan论文数: 0 引用数: 0 h-index: 0机构: Childrens Univ Hosp Brno, Dept Paediat Haematol, Brno 61300, Czech Republic Childrens Univ Hosp Brno, Dept Paediat Haematol, Brno 61300, Czech RepublicMathew, Prasad论文数: 0 引用数: 0 h-index: 0机构: Univ New Mexico, Dept Pediat, Albuquerque, NM 87131 USA Childrens Univ Hosp Brno, Dept Paediat Haematol, Brno 61300, Czech Republic论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:Fiamoli, Veronika论文数: 0 引用数: 0 h-index: 0机构: Childrens Univ Hosp Brno, Dept Paediat Haematol, Brno 61300, Czech Republic Childrens Univ Hosp Brno, Dept Paediat Haematol, Brno 61300, Czech Republic
- [12] Recombinant factor VIII products and inhibitor development in previously untreated boys with severe hemophilia A[J]. BLOOD, 2014, 124 (23) : 3398 - 3408Calvez, Thierry论文数: 0 引用数: 0 h-index: 0机构: Univ Paris 06, Sorbonne Univ, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, Paris, France INSERM, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, F-75646 Paris 13, France Univ Paris 06, Sorbonne Univ, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, Paris, FranceChambost, Herve论文数: 0 引用数: 0 h-index: 0机构: Assistance Publ Hop Marseille, Serv Hematol Oncol Pediat, Marseille, France Aix Marseille Univ, Fac Med, INSERM, UMR 1062, Marseille, France Univ Paris 06, Sorbonne Univ, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, Paris, FranceClaeyssens-Donadel, Segolene论文数: 0 引用数: 0 h-index: 0机构: Ctr Hosp Univ, Ctr Reg Hemophilie, Toulouse, France Univ Paris 06, Sorbonne Univ, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, Paris, France论文数: 引用数: h-index:机构:Goulet, Veronique论文数: 0 引用数: 0 h-index: 0机构: French Inst Publ Hlth Surveillance, St Maurice, France Univ Paris 06, Sorbonne Univ, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, Paris, FranceGuillet, Benoit论文数: 0 引用数: 0 h-index: 0机构: Ctr Hosp Univ Rennes, Ctr Reg Traitement Malad Hemorrag Rennes Bretagne, Rennes, France Univ Rennes 1, Fac Med, Rennes, France Univ Paris 06, Sorbonne Univ, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, Paris, FranceHeritier, Virginie论文数: 0 引用数: 0 h-index: 0机构: French Inst Publ Hlth Surveillance, St Maurice, France Univ Paris 06, Sorbonne Univ, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, Paris, FranceMilien, Vanessa论文数: 0 引用数: 0 h-index: 0机构: Assistance Publ Hop Marseille, Serv Hematol Oncol Pediat, Marseille, France Univ Paris 06, Sorbonne Univ, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, Paris, FranceRothschild, Chantal论文数: 0 引用数: 0 h-index: 0机构: Ctr Hosp Univ Necker, Assistance Publ Hop Paris, Ctr Reg Hemophilie, Paris, France Univ Paris 06, Sorbonne Univ, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, Paris, FranceRoussel-Robert, Valerie论文数: 0 引用数: 0 h-index: 0机构: Ctr Hosp Univ Cochin, Assistance Publ Hop Paris, Ctr Reg Hemophilie, Paris, France Univ Paris 06, Sorbonne Univ, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, Paris, FranceVinciguerra, Christine论文数: 0 引用数: 0 h-index: 0机构: Univ Lyon, Hosp Civils Lyon, Serv Hematol Biol, Equipe Accueil Mixte 4174, Lyon, France Univ Paris 06, Sorbonne Univ, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, Paris, FranceGoudemand, Jenny论文数: 0 引用数: 0 h-index: 0机构: Univ Lille 2, Ctr Hosp Univ Lille, Serv Hematol & Transfus, Equipe Accueil 2693,Fac Med, Lille, France Univ Paris 06, Sorbonne Univ, Unite Mixte Rech Sante 1136, Inst Pierre Louis Epidemiol & Sante Publ, Paris, France
- [13] Inhibitors in factor IX deficiency a report of the ISTH-SSC international FIX inhibitor registry (1997-2006)[J]. HAEMOPHILIA, 2009, 15 (05) : 1027 - 1031论文数: 引用数: h-index:机构:Warrier, I.论文数: 0 引用数: 0 h-index: 0机构: Wayne State Univ, Childrens Hosp Michigan, Detroit Med Ctr, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USA Wayne State Univ, Childrens Hosp Michigan, Detroit Med Ctr, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USA论文数: 引用数: h-index:机构:Lusher, J. M.论文数: 0 引用数: 0 h-index: 0机构: Wayne State Univ, Childrens Hosp Michigan, Detroit Med Ctr, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USA Wayne State Univ, Childrens Hosp Michigan, Detroit Med Ctr, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USA
- [14] Safety and pharmacokinetics of anti-TFPI antibody (concizumab) in healthy volunteers and patients with hemophilia: a randomized first human dose trial[J]. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2015, 13 (05) : 743 - 754Chowdary, P.论文数: 0 引用数: 0 h-index: 0机构: Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England Royal Free Hosp, Thrombosis Unit, London NW3 2QG, England Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, EnglandLethagen, S.论文数: 0 引用数: 0 h-index: 0机构: Novo Nordisk AS, Soborg, Denmark Univ Copenhagen, Copenhagen, Denmark Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, EnglandFriedrich, U.论文数: 0 引用数: 0 h-index: 0机构: Novo Nordisk AS, Soborg, Denmark Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, EnglandBrand, B.论文数: 0 引用数: 0 h-index: 0机构: Univ Zurich Hosp, Div Hematol, CH-8091 Zurich, Switzerland Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, EnglandHay, C.论文数: 0 引用数: 0 h-index: 0机构: Manchester Royal Infirm, Univ Dept Haematol, Manchester M13 9WL, Lancs, England Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, EnglandKarim, F. Abdul论文数: 0 引用数: 0 h-index: 0机构: Natl Blood Ctr, Haemophilia Ctr, Kuala Lumpur, Malaysia Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, EnglandKlamroth, R.论文数: 0 引用数: 0 h-index: 0机构: Vivantes Hosp Friedrichshain, Dept Internal Med Angiol Haemostasis & Coagulat D, Berlin, Germany Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, EnglandKnoebl, P.论文数: 0 引用数: 0 h-index: 0机构: Med Univ Vienna, Div Haematol & Haemostasis, Dept Med 1, Vienna, Austria Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England论文数: 引用数: h-index:机构:Mahlangu, J.论文数: 0 引用数: 0 h-index: 0机构: NHLS, Johannesburg, South Africa Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, EnglandMiesbach, W.论文数: 0 引用数: 0 h-index: 0机构: Univ Witwatersrand, Dept Mol Med & Haematol, Fac Hlth Sci, Johannesburg, South Africa Hamophilie Zentrum, Zentrum Innere Med, Med Klin 3, Frankfurt, Germany Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, EnglandNielsen, J. Dalsgaard论文数: 0 引用数: 0 h-index: 0机构: Rigshosp, Thrombosis & Haemostasis Unit, Dept Haematol, DK-2100 Copenhagen, Denmark Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, EnglandMartin-Salces, M.论文数: 0 引用数: 0 h-index: 0机构: Hosp Univ La Paz, Dept Haematol, Madrid, Spain Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, EnglandAngchaisuksiri, P.论文数: 0 引用数: 0 h-index: 0机构: Mahidol Univ, Ramathibodi Hosp, Fac Med, Div Hematol,Dept Med, Bangkok 10400, Thailand Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
- [15] Similar bleeding phenotype in young children with haemophilia A or B: a cohort study[J]. HAEMOPHILIA, 2014, 20 (06) : 747 - 755Clausen, N.论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Aarhus Skejby, Dept Pediat, DK-8200 Aarhus, Denmark Univ Hosp Aarhus Skejby, Dept Pediat, DK-8200 Aarhus, DenmarkPetrini, P.论文数: 0 引用数: 0 h-index: 0机构: Karolinska Hosp, Dept Pediat, Clin Coagulat Disorders, S-10401 Stockholm, Sweden Univ Hosp Aarhus Skejby, Dept Pediat, DK-8200 Aarhus, DenmarkClaeyssens-Donadel, S.论文数: 0 引用数: 0 h-index: 0机构: Ctr Hosp Univ, Ctr Reg Haemophilie, Toulouse, France Univ Hosp Aarhus Skejby, Dept Pediat, DK-8200 Aarhus, DenmarkGouw, S. C.论文数: 0 引用数: 0 h-index: 0机构: Univ Amsterdam, Acad Med Ctr, Emma Childrens Hosp, Dept Pediat Hematol, NL-1105 AZ Amsterdam, Netherlands Univ Hosp Aarhus Skejby, Dept Pediat, DK-8200 Aarhus, DenmarkLiesner, R.论文数: 0 引用数: 0 h-index: 0机构: Great Ormond St Hosp Children NHS Fdn Trust, Haemophilia Comprehens Care Ctr, London, England Univ Hosp Aarhus Skejby, Dept Pediat, DK-8200 Aarhus, Denmark
- [16] The use of enhanced half-life coagulation factor concentrates in routine clinical practice: guidance from UKHCDO[J]. HAEMOPHILIA, 2016, 22 (04) : 487 - 498Collins, P.论文数: 0 引用数: 0 h-index: 0机构: Univ Wales Hosp, Arthur Bloom Haemophilia Ctr, Cardiff, S Glam, Wales Univ Wales Hosp, Arthur Bloom Haemophilia Ctr, Cardiff, S Glam, WalesChalmers, E.论文数: 0 引用数: 0 h-index: 0机构: Royal Hosp Sick Children, Haemophilia Ctr, Glasgow, Lanark, Scotland Univ Wales Hosp, Arthur Bloom Haemophilia Ctr, Cardiff, S Glam, WalesChowdary, P.论文数: 0 引用数: 0 h-index: 0机构: Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London, England Univ Wales Hosp, Arthur Bloom Haemophilia Ctr, Cardiff, S Glam, WalesKeeling, D.论文数: 0 引用数: 0 h-index: 0机构: Churchill Hosp, Haemophilia Ctr, Oxford, England Univ Wales Hosp, Arthur Bloom Haemophilia Ctr, Cardiff, S Glam, WalesMathias, M.论文数: 0 引用数: 0 h-index: 0机构: Great Ormond St Hosp Sick Children, Haemophilia Ctr, London, England Univ Wales Hosp, Arthur Bloom Haemophilia Ctr, Cardiff, S Glam, WalesO'Donnell, J.论文数: 0 引用数: 0 h-index: 0机构: St James Hosp, Haemophilia Ctr, Dublin, Ireland Univ Wales Hosp, Arthur Bloom Haemophilia Ctr, Cardiff, S Glam, WalesPasi, K. J.论文数: 0 引用数: 0 h-index: 0机构: Royal London Hosp, Haemophilia Ctr, London, England Univ Wales Hosp, Arthur Bloom Haemophilia Ctr, Cardiff, S Glam, WalesRangarajan, S.论文数: 0 引用数: 0 h-index: 0机构: Basingstoke & North Hampshire Hosp, Haemophilia Ctr, Basingstoke, Hants, England Univ Wales Hosp, Arthur Bloom Haemophilia Ctr, Cardiff, S Glam, WalesThomas, A.论文数: 0 引用数: 0 h-index: 0机构: Royal Infirm Edinburgh NHS Trust, Haemophilia Ctr, Edinburgh, Midlothian, Scotland Univ Wales Hosp, Arthur Bloom Haemophilia Ctr, Cardiff, S Glam, Wales
- [17] Factor VIII brand and the incidence of factor VIII inhibitors in previously untreated UK children with severe hemophilia A, 2000-2011[J]. BLOOD, 2014, 124 (23) : 3389 - 3397Collins, Peter W.论文数: 0 引用数: 0 h-index: 0机构: Univ Wales Hosp, Dept Haematol, Sch Med, Cardiff CF14 4XN, S Glam, Wales Univ Wales Hosp, Dept Haematol, Sch Med, Cardiff CF14 4XN, S Glam, WalesPalmer, Benedict P.论文数: 0 引用数: 0 h-index: 0机构: UK Natl Haemophilia Database, Manchester, Lancs, England Univ Wales Hosp, Dept Haematol, Sch Med, Cardiff CF14 4XN, S Glam, WalesChalmers, Elizabeth A.论文数: 0 引用数: 0 h-index: 0机构: Royal Hosp Sick Children, Dept Haematol, Glasgow G3 8SJ, Lanark, Scotland Univ Wales Hosp, Dept Haematol, Sch Med, Cardiff CF14 4XN, S Glam, WalesHart, Daniel P.论文数: 0 引用数: 0 h-index: 0机构: Queen Mary Univ London, Barts & London Sch Med & Dent, Haemophilia Ctr, Royal London Hosp, London, England Univ Wales Hosp, Dept Haematol, Sch Med, Cardiff CF14 4XN, S Glam, WalesLiesner, Ri论文数: 0 引用数: 0 h-index: 0机构: Great Ormond St Hosp Children Natl Hlth Serv Fdn, Haemophilia Ctr, London, England Univ Wales Hosp, Dept Haematol, Sch Med, Cardiff CF14 4XN, S Glam, WalesRangarajan, Savita论文数: 0 引用数: 0 h-index: 0机构: Guys & St Thomas Hosp, Ctr Haemostasis & Thrombosis, London, England Hampshire Hosp Natl Hlth Serv Fdn Trust, Haemophilia Haemostasis & Thrombosis Ctr, Basingstoke, Hants, England Univ Wales Hosp, Dept Haematol, Sch Med, Cardiff CF14 4XN, S Glam, WalesTalks, Katherine论文数: 0 引用数: 0 h-index: 0机构: Royal Victoria Infirm, Dept Haematol, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England Univ Wales Hosp, Dept Haematol, Sch Med, Cardiff CF14 4XN, S Glam, WalesWilliams, Michael论文数: 0 引用数: 0 h-index: 0机构: Birmingham Childrens Hosp Natl Hlth Serv Fdn Trus, Dept Haematol, Birmingham, W Midlands, England Univ Wales Hosp, Dept Haematol, Sch Med, Cardiff CF14 4XN, S Glam, WalesHay, Charles R. M.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Manchester Royal Infirm, Dept Haematol, Manchester M13 9WL, Lancs, England Univ Wales Hosp, Dept Haematol, Sch Med, Cardiff CF14 4XN, S Glam, Wales
- [18] Thrombotic adverse events to coagulation factor concentrates for treatment of patients with haemophilia and von Willebrand disease: a systematic review of prospective studies[J]. HAEMOPHILIA, 2012, 18 (03) : e173 - e187Coppola, A.论文数: 0 引用数: 0 h-index: 0机构: Federico II Univ Hosp, Dept Clin & Expt Med, Reg Reference Ctr Coagulat Disorders, Naples, Italy IRCCS Ca Granda Fdn, Maggiore Policlin Hosp, Sci Direct, I-20122 Milan, ItalyFranchini, M.论文数: 0 引用数: 0 h-index: 0机构: Carlo Poma Hosp, Dept Transfus Med & Hematol, Mantua, Italy IRCCS Ca Granda Fdn, Maggiore Policlin Hosp, Sci Direct, I-20122 Milan, Italy论文数: 引用数: h-index:机构:Santagostino, E.论文数: 0 引用数: 0 h-index: 0机构: IRCCS Ca Granda Fdn, Maggiore Policlin Hosp, A Bianchi Bonomi Hemophilia & Thrombosis Ctr, I-20122 Milan, Italy IRCCS Ca Granda Fdn, Maggiore Policlin Hosp, Sci Direct, I-20122 Milan, ItalyDi Minno, G.论文数: 0 引用数: 0 h-index: 0机构: Federico II Univ Hosp, Dept Clin & Expt Med, Reg Reference Ctr Coagulat Disorders, Naples, Italy IRCCS Ca Granda Fdn, Maggiore Policlin Hosp, Sci Direct, I-20122 Milan, ItalyMannucci, P. M.论文数: 0 引用数: 0 h-index: 0机构: IRCCS Ca Granda Fdn, Maggiore Policlin Hosp, Sci Direct, I-20122 Milan, Italy IRCCS Ca Granda Fdn, Maggiore Policlin Hosp, Sci Direct, I-20122 Milan, Italy
- [19] Mortality rates, life expectancy, and causes of death in people with hemophilia A or B in the United Kingdom who were not infected with HIV[J]. BLOOD, 2007, 110 (03) : 815 - 825Darby, Sarah C.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Manchester Royal Infirm, Dept Haematol, Manchester M13 9WL, Lancs, EnglandKan, Sau Wan论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Manchester Royal Infirm, Dept Haematol, Manchester M13 9WL, Lancs, EnglandSpooner, Rosemary J.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Manchester Royal Infirm, Dept Haematol, Manchester M13 9WL, Lancs, EnglandGiangrande, Paul L. F.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Manchester Royal Infirm, Dept Haematol, Manchester M13 9WL, Lancs, EnglandHill, Frank G. H.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Manchester Royal Infirm, Dept Haematol, Manchester M13 9WL, Lancs, EnglandHay, Charles R. M.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Manchester Royal Infirm, Dept Haematol, Manchester M13 9WL, Lancs, EnglandLee, Christine A.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Manchester Royal Infirm, Dept Haematol, Manchester M13 9WL, Lancs, EnglandLudlam, Christopher A.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Manchester Royal Infirm, Dept Haematol, Manchester M13 9WL, Lancs, England论文数: 引用数: h-index:机构:
- [20] International workshop on immune tolerance induction: consensus recommendations[J]. HAEMOPHILIA, 2007, 13 : 1 - 22Dimichele, D. M.论文数: 0 引用数: 0 h-index: 0机构: Cornell Univ, Weill Med Coll, Dept Pediat, New York, NY 10021 USAHoots, W. K.论文数: 0 引用数: 0 h-index: 0机构: Cornell Univ, Weill Med Coll, Dept Pediat, New York, NY 10021 USAPipe, S. W.论文数: 0 引用数: 0 h-index: 0机构: Cornell Univ, Weill Med Coll, Dept Pediat, New York, NY 10021 USARivard, G. E.论文数: 0 引用数: 0 h-index: 0机构: Cornell Univ, Weill Med Coll, Dept Pediat, New York, NY 10021 USASantagostino, E.论文数: 0 引用数: 0 h-index: 0机构: Cornell Univ, Weill Med Coll, Dept Pediat, New York, NY 10021 USA