Antibody-Modified Reduced Graphene Oxide Films with Extreme Sensitivity to Circulating Tumor Cells

被引:132
|
作者
Li, Yingying [1 ,2 ]
Lu, Qihang [1 ]
Liu, Hongliang [3 ]
Wang, Jianfeng [4 ]
Zhang, Pengchao [1 ,2 ]
Liang, Huageng [5 ]
Jiang, Lei [1 ,4 ]
Wang, Shutao [1 ,3 ]
机构
[1] Chinese Acad Sci, Key Lab Organ Solids Inst Chem, Beijing Natl Lab Mol Sci BNLMS, Beijing 100190, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[3] Chinese Acad Sci, Tech Inst Phys & Chem, Lab Bioinspired Smart Interface Sci, Beijing 100190, Peoples R China
[4] Beihang Univ, Sch Chem & Environm, Beijing 100191, Peoples R China
[5] Huazhong Univ Sci & Technol, Tongji Med Coll, Union Hosp, Wuhan 430022, Hubei Province, Peoples R China
基金
国家高技术研究发展计划(863计划); 中国国家自然科学基金;
关键词
FUNCTIONALIZED GRAPHENE; CAPTURE; REDUCTION;
D O I
10.1002/adma.201502615
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An antibody-modified reduced graphene oxide (rGO) film with unexpected extreme sensitivity to circulating tumor cells (CTCs) is reported. The antibody-modified rGO films efficiently capture CTCs from billions of blood cells and minimize the background of white blood cells, without complex microfluidic operations.
引用
收藏
页码:6848 / +
页数:8
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