Antibody-Modified Reduced Graphene Oxide Films with Extreme Sensitivity to Circulating Tumor Cells

被引:132
|
作者
Li, Yingying [1 ,2 ]
Lu, Qihang [1 ]
Liu, Hongliang [3 ]
Wang, Jianfeng [4 ]
Zhang, Pengchao [1 ,2 ]
Liang, Huageng [5 ]
Jiang, Lei [1 ,4 ]
Wang, Shutao [1 ,3 ]
机构
[1] Chinese Acad Sci, Key Lab Organ Solids Inst Chem, Beijing Natl Lab Mol Sci BNLMS, Beijing 100190, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[3] Chinese Acad Sci, Tech Inst Phys & Chem, Lab Bioinspired Smart Interface Sci, Beijing 100190, Peoples R China
[4] Beihang Univ, Sch Chem & Environm, Beijing 100191, Peoples R China
[5] Huazhong Univ Sci & Technol, Tongji Med Coll, Union Hosp, Wuhan 430022, Hubei Province, Peoples R China
基金
国家高技术研究发展计划(863计划); 中国国家自然科学基金;
关键词
FUNCTIONALIZED GRAPHENE; CAPTURE; REDUCTION;
D O I
10.1002/adma.201502615
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An antibody-modified reduced graphene oxide (rGO) film with unexpected extreme sensitivity to circulating tumor cells (CTCs) is reported. The antibody-modified rGO films efficiently capture CTCs from billions of blood cells and minimize the background of white blood cells, without complex microfluidic operations.
引用
收藏
页码:6848 / +
页数:8
相关论文
共 50 条
  • [21] Characterization of Graphene Oxide and Reduced Graphene Oxide/Metal Oxide Nanocomposite Thin Films
    Mohi, Linda I.
    Abdulameer, Ameer F.
    INTERNATIONAL JOURNAL OF NANOSCIENCE, 2024, 23 (01)
  • [22] Boiling characteristics on the reduced graphene oxide films
    Ahn, Ho Seon
    Kim, Ji Min
    Kim, Jin Man
    Park, Su Cheong
    Hwang, Kyungwon
    Jo, Hang Jin
    Kim, TaeJoo
    Jerng, Dong Wook
    Kaviany, Massoud
    Kim, Moo Hwan
    EXPERIMENTAL THERMAL AND FLUID SCIENCE, 2015, 60 : 361 - 366
  • [23] Large and pristine films of reduced graphene oxide
    Ahn, Sung Il
    Kim, Kukjoo
    Jung, Jura
    Choi, Kyung Cheol
    SCIENTIFIC REPORTS, 2015, 5
  • [24] The Kondo effect in reduced graphene oxide films
    McIntosh, Ross
    Bhattacharyya, Somnath
    PHYSICA STATUS SOLIDI-RAPID RESEARCH LETTERS, 2012, 6 (02): : 56 - 58
  • [25] Terahertz conductivity of reduced graphene oxide films
    Hong, J. T.
    Lee, K. M.
    Son, B. H.
    Park, S. J.
    Park, D. J.
    Park, Ji-Yong
    Lee, Soonil
    Ahn, Y. H.
    OPTICS EXPRESS, 2013, 21 (06): : 7633 - 7640
  • [26] Large and pristine films of reduced graphene oxide
    Sung Il Ahn
    Kukjoo Kim
    Jura Jung
    Kyung Cheol Choi
    Scientific Reports, 5
  • [27] Enhancing the corrosion resistance of aluminum by graphene oxide and reduced graphene oxide films
    Badr, Atefeh
    Sadighi, Mandieh
    Asgharzadeh, Hamed
    Rabizadeh, Taher
    MATERIALS RESEARCH EXPRESS, 2019, 6 (07)
  • [28] Synthesis and characterization of nanocomposites films with graphene oxide and reduced graphene oxide nanosheets
    Goumri, Meryem
    Poilane, Christophe
    Ruterana, Pierre
    Ben Doudou, Bessem
    Wery, Jany
    Bakour, Anass
    Baitoul, Mimouna
    CHINESE JOURNAL OF PHYSICS, 2017, 55 (02) : 412 - 422
  • [29] Tumor targeting of doxorubicin by anti-MT1-MMP antibody-modified PEG liposomes
    Hatakeyama, Hiroto
    Akita, Hidetaka
    Ishida, Emi
    Hashimoto, Koichi
    Kobayashi, Hideo
    Aoki, Takanori
    Yasuda, Junko
    Obata, Kenichi
    Kikuchi, Hiroshi
    Ishida, Tatsuhiro
    Kiwada, Hiroshi
    Harashima, Hideyoshi
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2007, 342 (1-2) : 194 - 200
  • [30] Electrical and Optical Characterization of Graphene Oxide and Reduced Graphene Oxide Thin Films
    Politano, Grazia Giuseppina
    Versace, Carlo
    CRYSTALS, 2022, 12 (09)