Synthesis and Antifungal Activity of 1,3,4-Thiadiazole Derivatives Containing Pyridine Group

被引：107
|
作者：
Zhang, Lin-Jiong [1 ]
Yang, Ming-Yan [1 ]
Sun, Zhao-Hui [1 ]
Tan, Cheng-Xia [1 ]
Weng, Jian-Quan [1 ]
Wu, Hong-Ke [1 ]
Liu, Xing-Hai [1 ]
机构：
[1] Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Zhejiang, Peoples R China
来源：
LETTERS IN DRUG DESIGN & DISCOVERY | 2014年 / 11卷 / 09期
基金：
中国国家自然科学基金;
关键词：
1,3,4-thiadiazole; antifungal activity; pyridine; synthesis; CRYSTAL-STRUCTURE; BIOLOGICAL EVALUATION; 1,2,4-TRIAZOLE DERIVATIVES; ANTIMICROBIAL ACTIVITIES; FUNGICIDAL ACTIVITY; DESIGN; BIOACTIVITY; ANTICONVULSANT; DOCKING; MOIETY;
D O I：
10.2174/1570180811666140610212731
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Some 1,3,4-thiadiazole derivatives containing pyridine group were synthesized. The structures of 1,3,4-thiadiazoles were confirmed by H-1 NMR, MS, and elemental analysis. The title compounds were investigated for antifungal activities. The results showed that some of them exhibited good antifungal activity.
引用
收藏
页码：1107 / 1111
页数：5
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