New Efficient Synthesis of 5-Ethoxyoxazoles and Oxazolo[3,2-c]quinazolines via Aza-Wittig Reaction

被引：19
|
作者：
Huang, Nian-Yu [1 ]
Nie, Yi-Bo [1 ]
Ding, Ming-Wu [1 ]
机构：
[1] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China
来源：
SYNLETT | 2009年 / 04期
基金：
中国国家自然科学基金;
关键词：
oxazole; oxazolo[3,2-c]quinazoline; aza Wittig reaction; carbodiimide; imidoyl chloride; IMINOPHOSPHORANE-MEDIATED SYNTHESIS; FACILE SYNTHESIS; OXAZOLES; ROUTE;
D O I：
10.1055/s-0028-1087562
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
5-Ethoxyoxazoles or 2-acylamino propanoates were synthesized by aza-Wittig reaction of iminophosphorane with acyl chloride in the presence of triethylamine. Reactions of 5-alkoxyoxazole with triphenyphosphine produced iminophosphoranes. A tandem aza-Wittig reaction of iminophosphorane with isocyanate or carbon disulfide generated oxazolo[3,2-c]quinazolines in satisfactory yields.
引用
收藏
页码：611 / 614
页数：4
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