Unmasked Acyl Anion Equivalent from Acid Chloride with Indium: Reversed-Polarity Synthesis of Unsymmetric Aryl Aryl and Alkenyl Aryl Ketone through Palladium-Catalyzed Cross-Coupling Reaction

被引：41
|
作者：
Lee, Dohyung [1 ]
Ryu, Taekyu [1 ]
Park, Youngchul [1 ]
Lee, Phil Ho [1 ]
机构：
[1] Kangwon Natl Univ, Dept Chem, Chunchon 200701, South Korea
来源：
ORGANIC LETTERS | 2014年 / 16卷 / 04期
基金：
新加坡国家研究基金会;
关键词：
ELECTRON-RICH OLEFINS; CARBON BOND FORMATION; GENERATED IN-SITU; DIRECT ACYLATION; ACYLZIRCONOCENE CHLORIDE; COOPERATIVE CATALYSIS; ORGANOINDIUM REAGENTS; CONVENIENT ROUTE; ALLYLIC ESTERS; HECK ARYLATION;
D O I：
10.1021/ol500003g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A reversed-polarity synthetic method of a range of unsymmetric aryl aryl and alkenyl aryl ketones has been developed through Pd-catalyzed cross-coupling reaction of acylindium reagents generated in situ from easily available acid chlorides and indium with various electrophiles such as aryl iodide and triflate and alkenyl triflate.
引用
收藏
页码：1144 / 1147
页数：4
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