Suitably functionalised pyrimidines as potential antimycotic agents

被引:68
作者
Agarwal, N
Raghuwanshi, SK
Upadhyay, DN
Shukla, PK
Ram, VJ [1 ]
机构
[1] Cent Drug Res Inst, Div Med Chem, Lucknow 226001, Uttar Pradesh, India
[2] Cent Drug Res Inst, Div Med Mycol, Lucknow 226001, Uttar Pradesh, India
关键词
D O I
10.1016/S0960-894X(00)00091-3
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Various suitably functionalised pyrimidine derivatives have been synthesized to explore their potential as antimycotic agents. Some of the synthesized compounds 4c, 4d, 8a-e have shown highly significant in vitro antifungal activity against five human pathogenic fungi. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:703 / 706
页数:4
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