Isolation of lappaconitine from Aconitum septentrionale roots by adsorption

被引：10
作者：
Goncharov, A. E.
Politov, A. A.
Pankrushina, N. A.
Lomovskii, O. I.
机构：
[1] Novosibirsk State Univ, Novosibirsk 630090, Russia
[2] Russian Acad Sci, Siberian Div, Inst Solid State & Mech Chem, Novosibirsk 630090, Russia
[3] Russian Acad Sci, Siberian Div, Inst Organ Chem, Novosibirsk 630090, Russia
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2006年 / 42卷 / 03期
关键词：
lappaconitine; Aconitum septentrionale; diterpene alkaloids; adsorptive isolation; extraction; Al2O3;
D O I：
10.1007/s10600-006-0114-6
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Extracts of Aconitum septentrionale Koelle roots obtained using chloroform, isopropanol, and ethanol were purified using chloroform and basic gamma-Al2O3. Ballast materials were selectively adsorbed by gamma-Al2O3, increasing the mass fraction of lappaconitine in the extract. The ethanol extract was purified most. The degree of lappaconitine extraction by chloroform was unaffected by the presence of gamma-Al2O3. However, the mass fraction in the extract and lappaconitine extraction from Aconitum septentrionale were increased more than twice.
引用
收藏
页码：336 / 339
页数：4
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