New perspectives on the biology and treatment of X-linked hypophosphatemic rickets

被引：87
作者：
Carpenter, TO [1 ]
机构：
[1] YALE NEW HAVEN MED CTR, NEW HAVEN, CT 06504 USA
来源：
PEDIATRIC CLINICS OF NORTH AMERICA | 1997年 / 44卷 / 02期
关键词：
D O I：
10.1016/S0031-3955(05)70485-5
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
This article updates the practicing pediatrician's knowledge of the hypophophatemic disorders that may occur in children. The classic X-Linked disorder is emphasized. Details of clinical manifestations, the wide spectrum of disease severity, and complications of the disorder in adults are reviewed. Recent research, new genetic findings, and speculations regarding pathophysiology are discussed. A strategy for approaching medical treatment of X-linked hypophosphatemic rickets is provided, together with complications of treatment and treatment after cessation of growth.
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页码：443 / +
页数：1
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