A palladium-catalyzed route to chiral 1,2,3-trisubstituted cyclopropanes

被引：0

作者：

Michelet, V ^{[1
]}

Genet, JP ^{[1
]}

机构：

[1] ECOLE NATL SUPER CHIM,ORGAN SYNTH LAB,CNRS,F-75231 PARIS 05,FRANCE

来源：

BULLETIN DE LA SOCIETE CHIMIQUE DE FRANCE | 1996年 / 133卷 / 09期

关键词：

alkylation; cyclopropanation; decarboalkoxylation; palladium(0) catalyst; chiral vinylic cyclopropane;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An easy and efficient method for the synthesis of 1,2,3-trisubstituted vinylic cyclopropanes is described. The key steps are alkylation of chiral allylic alcohols, cyclization of functionalized allylic substates using a palladium(0) catalyst and decarboalkoxylation.

引用

页码：881 / 889

页数：9

共 44 条

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