Fluorine-Containing Benzimidazoles and Their [a]- and [b]Heteroannelated Derivatives: Synthesis and Biological Activity (Review)

被引：9
作者：
Lipunova, G. N. [1 ,2 ]
Nosova, E. V. [2 ]
Charushin, V. N. [1 ,2 ]
机构：
[1] Russian Acad Sci, Ural Branch, I Ya Postovskii Inst Organ Synth, Ekaterinburg 620219, Russia
[2] Ural Fed Univ, Ekaterinburg 620002, Russia
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2014年 / 50卷 / 06期
基金：
俄罗斯基础研究基金会;
关键词：
fluorobenzimidazoles; nucleosides; annelation; biological activity; cycloaddition; cyclocondensation; ONE-POT SYNTHESIS; NITROANILINE DERIVATIVES; HUMAN CYTOMEGALOVIRUS; RNA DUPLEXES; N-YLIDES; INHIBITORS; ACID; NUCLEOSIDES; AGENTS; FLUOROQUINOLONES;
D O I：
10.1007/s10593-014-1533-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Published data from 1992-2013 on methods for the synthesis and biological activity of fluorine-containing benzimidazoles and their [a]- and [b]heteroannelated derivatives are summarized and classified.
引用
收藏
页码：764 / 790
页数：27
相关论文
共 81 条
[1]   Pharmacokinetics, metabolism and interactions of acid pump inhibitors - Focus on omeprazole, lansoprazole and pantoprazole [J].
Andersson, T .
CLINICAL PHARMACOKINETICS, 1996, 31 (01) :9-28
[2]  
ASLANIAN RG, 2008, Patent No. 2008108958
[3]  
AXELSSON O, Patent No. 0563001
[4]   BENZIMIDAZOLE CONDENSED RING-SYSTEM .9. POTENTIAL ANTINEOPLASTICS - NEW SYNTHESIS OF SOME PYRIDO[1,2-A]BENZIMIDAZOLES AND RELATED DERIVATIVES [J].
BADAWEY, E ;
KAPPE, T .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1995, 30 (04) :327-332
[5]  
BARRETT SD, 2005, Patent No. 2005009975
[6]  
BARRETT SD, Patent No. 0105390
[7]  
BARRETT SD, Patent No. 0042022
[8]  
BATEMAN NF, 2009, Patent No. 2009118562
[9]   ALKYLATING ACTIVITY OF POLYPHOSPHATE ESTER IN THE COURSE OF THE SYNTHESIS OF BENZIMIDAZOLES [J].
BISTOCCHI, GA ;
DEMEO, G ;
PEDINI, M ;
RICCI, A ;
JACQUIGNON, P .
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1985, 50 (09) :1959-1961
[10]  
BOUZARD D, 1993, ANTIBIOTICS ANTIVIRA, P187
123456789