DIFFUSE BONE MARROW METASTASIS IN CEREBELLAR HIGH-GRADE ASTROCYTOMA. A CASE REPORT

被引：1

作者：

Freitas, M. R. P. ^{[1
]}

de Muzio, S. D. C. ^{[2
]}

Pessoa, R. C. C. ^{[3
]}

Stavale, J. N. ^{[4
]}

Borges, L. R. R. ^{[5
]}

Malheiros, S. M. F. ^{[5
]}

机构：

[1] Univ Fed Sao Paulo, Dept Oncol, Escola Paulista Med, BR-04023900 Sao Paulo, Brazil

[2] Univ Fed Sao Paulo, Dept Neurocirurgia, Escola Paulista Med, BR-04023900 Sao Paulo, Brazil

[3] Univ Fed Sao Paulo, Dept Radiol, Escola Paulista Med, BR-04023900 Sao Paulo, Brazil

[4] Univ Fed Sao Paulo, Dept Patol, Escola Paulista Med, BR-04023900 Sao Paulo, Brazil

[5] Univ Fed Sao Paulo, Dept Neurol, Escola Paulista Med, BR-04023900 Sao Paulo, Brazil

来源：

REVISTA DE NEUROLOGIA | 2009年 / 48卷 / 05期

关键词：

Anaplastic astrocytoma; Bone marrow metastases; Extraneural metastases; Gliomas; Malignant astrocytoma; Pancytopenia; GLIOBLASTOMA-MULTIFORME; EXTRACRANIAL METASTASES; GLIOMAS;

D O I：

10.33588/rn.4805.2008202

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction. Cerebellar high-grade astrocytoma is uncommon. Although more prone to present cerebrospinal fluid dissemination, the cerebellar location is not particularly related to the occurrence of extra-cranial metastases, which are also unusual in supratentorial malignant gliomas. Case report. A 46 year-old man with cerebellar anaplastic astrocytoma who developed pancytopenia due to extensive bone marrow metastases. Conclusion. Extraneural metastases of brain gliomas are rare and the spread to the bone marrow confers an extremely poor prognosis for these patients. The expected improvement in glioma patients' survival due to the combination of more efficient therapies may lead to an increased incidence of this uncommon presentation, justifying a more rigorous follow-up of systemic manifestations. [REV NEUROL 2009; 48: 242-4]

引用

页码：242 / 244

页数：3

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