Regulated cell death in diagnostic histopathology

被引：3

作者：

Skenderi, Faruk ^{[1
]}

Vranic, Semir ^{[1
]}

Damjanov, Ivan ^{[2
]}

机构：

[1] Univ Sarajevo, Ctr Clin, Dept Pathol, Sarajevo 71000, Bosnia & Herceg

[2] Univ Kansas, Sch Med, Dept Pathol & Lab Med, Kansas City, KS 66160 USA

来源：

INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY | 2015年 / 59卷 / 1-3期

关键词：

regulated cell death; programmed cell death; apoptosis; histopathology; diagnostic markers; PROGNOSTIC-SIGNIFICANCE; APOPTOTIC INDEX; BREAST-CANCER; UROTHELIAL CARCINOMA; ACTIVATED CASPASE-3; PARAFFIN SECTIONS; WILD-TYPE; IN-SITU; EXPRESSION; P53;

D O I：

10.1387/ijdb.150037fs

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Regulated cell death (RCD) is a controlled cellular process, essential for normal development,tissue integrity and homeostasis, and its dysregulation has been implicated in the pathogenesis of various conditions including developmental and immunological disorders, neurodegenerative diseases, and cancer. In this review, we briefly discuss the historical perspective and conceptual development of RCD, we overview recent classifications and some of the key players in RCD; finally we focus on current applications of RCD in diagnostic histopathology.

引用

页码：149 / 158

页数：10

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