Ruthenium-catalyzed synthesis of β-oxo esters in aqueous medium: Scope and limitations

被引：40
作者：
Cadierno, Victorio [1 ]
Francos, Javier [1 ]
Gimeno, Jose [1 ]
机构：
[1] Univ Oviedo, Dept Quim Organ & Inorgan, IUQOEM, CSIC,Unidad Asociada, E-33006 Oviedo, Spain
来源：
GREEN CHEMISTRY | 2010年 / 12卷 / 01期
关键词：
TRANSITION-METAL-COMPLEXES; HIGHLY EFFICIENT CATALYSTS; ANTI-ANDROGENIC ACTIVITY; ALLYLIC ALCOHOLS; PROPARGYLIC ALCOHOLS; ORGANIC-REACTIONS; CARBOXYLIC-ACIDS; CARBONYL-COMPOUNDS; TERMINAL ALKYNES; BOND FORMATIONS;
D O I：
10.1039/b914774h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The ability of the hydrosoluble ruthenium(II)complexes [RuCl2(eta(6)-arene)(PTA)] 3a-d, [RuCl2(eta(6)-arene)(PTA-Bn)] 4a-d, [RuCl2(eta(6)-arene)(DAPTA)] 5a-d, [RuCl2(eta(6)-arene)(TPPMS)] 6a-d (arene = C6H6, p-cymene, 1,3,5-C6H3Me3, C6Me6) to promote the atom-economic formation of beta-oxo esters, by addition of carboxylic acids to terminal propargylic alcohols in water has been explored. Scope, limitations and catalyst recycling have been evaluated using the most active catalyst [RuCl2(eta(6)-C6H6)(TPPMS)], 6a.
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收藏
页码：135 / 143
页数：9
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