Human milk oligosaccharides: prebiotics and beyond

被引：225

作者：

Bode, Lars ^{[1
]}

机构：

[1] Univ Calif San Diego, Sch Med, Div Neonatol, Dept Pediat, San Diego, CA 92103 USA

来源：

NUTRITION REVIEWS | 2009年 / 67卷 / 11期

关键词：

human milk oligosaccharides; infant formula; prebiotics; ACTIVATING-FACTOR-ACETYLHYDROLASE; 1ST; 6; MONTHS; NECROTIZING ENTEROCOLITIS; DC-SIGN; INFANTS; FORMULA; DIARRHEA; RISK; HIV; SUPPLEMENTATION;

D O I：

10.1111/j.1753-4887.2009.00239.x

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Human milk oligosaccharides (HMO) are complex glycans that are present at very high concentrations in human milk but not in infant formula. The significant energy expended by mothers to make these complex glycans suggests they must be important. How do maternal HMOs benefit the breast-fed infant? How are HMOs synthesized in the human mammary gland? How can we provide formula-fed infants with HMOs or HMO-like glycans? This article reviews current knowledge and open questions on the biosynthesis and functions of HMOs.

引用

页码：S183 / S191

页数：9

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