Zinc fingers: DNA binding and protein-protein interactions

被引:1
作者
Leon, O
Roth, M
机构
[1] Univ Austral Chile, Fac Ciencias, Inst Bioquim, Valdivia, Chile
[2] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Dept Biochem, Piscataway, NJ 08854 USA
关键词
zinc fingers; DNA binding; protein-protein interactions;
D O I
暂无
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The zinc finger domain is a very ubiquitous structural clement whose hallmark is the coordination of a zinc atom by several amino acid residues (cysteines and histidines, and occasionally aspartate and glutamate). These structural elements are associated with protein-nucleic acid recognition as well as protein-protein interactions. The pul pose of this review is to examine recent data on the DNA and protein binding properties of a few zinc fingers whose three dimensional structure is known.
引用
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页码:21 / 30
页数:10
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