Single source precursor synthesized CuS nanoparticles for NIR phototherapy of cancer and photodegradation of organic carcinogen

被引:26
作者
Arshad, Mehwish [1 ]
Wang, Zhaojie [2 ]
Nasir, Jamal Abdul [1 ]
Amador, Eric [3 ]
Jin, Mingwu [3 ]
Li, Haibin [3 ]
Chen, Zhigang [2 ]
Rehman, Zia Ur [1 ]
Chen, Wei [3 ]
机构
[1] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan
[2] Donghua Univ, Coll Mat Sci & Engn, Shanghai 201620, Peoples R China
[3] Univ Texas Arlington, Dept Phys, POB 19059, Arlington, TX 76019 USA
关键词
CuS nanoparticles; Carcinogen; Photocatalysis; Phototherapy; Anticancer; REDUCED GRAPHENE OXIDE; COPPER SULFIDE; CATALYTIC-REDUCTION; MAGNETIC NANOPARTICLES; SODIUM-BOROHYDRIDE; NANOCRYSTALS; 4-NITROPHENOL; CDS; NITROPHENOLS; SURFACE;
D O I
10.1016/j.jphotobiol.2020.112084
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Herein, we report cost effective and body compatible CuS nanoparticles (NPs) derived from a single source precursor as photothermal agent for healing deep cancer and photocatalytic remediation of organic carcinogens. These NPs efficiently kill MCF7 cells (both in vivo and in vitro) under NIR irradiation by raising the temperature of tumor cells. Such materials can be used for the treatment of deep cancer as they can produce a heating effect using high wavelength and deeply penetrating NIR radiation. Furthermore, CuS NPs under solar light irradiation efficiently convert p-nitrophenol (PNP), an environmental carcinogen, to p-aminophenol (PAP) of pharmaceutical implication. In a nutshell, CuS can be used for the treatment of deep cancer and for the remediation of carcinogenic pollutants. There seems an intrinsic connection between the two functions of CuS NPs that need to be explored in length.
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页数:9
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