Application of calcium phosphate nanoparticles in biomedicine

被引：276
|
作者：
Epple, M. [1 ]
Ganesan, K. [1 ]
Heumann, R. [2 ]
Klesing, J. [1 ]
Kovtun, A. [1 ]
Neumann, S. [2 ]
Sokolova, V. [1 ]
机构：
[1] Univ Duisburg Essen, Inorgan Chem & Ctr Nanointegrat Duisburg Essen, D-45117 Essen, Germany
[2] Univ Bochum, Fac Chem & Biochem, D-44780 Bochum, Germany
来源：
JOURNAL OF MATERIALS CHEMISTRY | 2010年 / 20卷 / 01期
关键词：
DRUG-DELIVERY; INORGANIC NANOPARTICLES; RNA INTERFERENCE; GENE DELIVERY; NANOCOMPOSITE PARTICLES; PHOTODYNAMIC THERAPY; FLUORESCENT-PROBES; MAMMALIAN-CELLS; DNA; CANCER;
D O I：
10.1039/b910885h
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Calciumphosphate has excellent biocompatibility due to its chemical similarity to human hard tissue (bone and teeth). In nanoparticulate dispersed form, it can be used as a carrier in biological systems, e. g. to transfer nucleic acids or drugs. If such nanoparticles are suitably functionalized with fluorescing dyes, they can also be used for imaging or for photodynamic therapy.
引用
收藏
页码：18 / 23
页数：6
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