No influence of GB virus C replication on the prognosis in a cohort of HIV-1-infected patients

被引:52
作者
Birk, M [1 ]
Lindbäck, S
Lidman, C
机构
[1] Huddinge Univ Hosp, Dept Infect Dis, Stockholm, Sweden
[2] Huddinge Univ Hosp, Karolinska Inst, Dept Clin Virol, Stockholm, Sweden
关键词
D O I
10.1097/00002030-200212060-00017
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Co-infection with GB virus C (GBV-C) in HIV-1-infected individuals could have a beneficial influence on disease outcome. We followed 157 HIV-1-infected patients with seroconversion dates defined within +/-1 year for a median of 7 years. Of these patients, 36 (23%) were positive for GBV-C RNA. Life-table analyses showed no significant difference in outcome variables between patients with or without GBV-C viraemia. Endpoints were CD4 T lymphocyte count of 200 cells/mul or less, AIDS diagnosis and AIDS-related death.
引用
收藏
页码:2482 / 2485
页数:4
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