Effect of blood transfusions on cerebral haemodynamics in preterm infants

被引：37

作者：

Dani, C ^{[1
]}

Pezzati, M ^{[1
]}

Martelli, E ^{[1
]}

Prussi, C ^{[1
]}

Bertini, G ^{[1
]}

Rubaltelli, FF ^{[1
]}

机构：

[1] Univ Florence, Sch Med, Careggi Univ Hosp, Div Neonatol, IT-50134 Florence, Italy

来源：

ACTA PAEDIATRICA | 2002年 / 91卷 / 09期

关键词：

anaemia; cerebral blood flow; Doppler; near infrared spectroscopy;

D O I：

10.1080/080352502760272623

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Aim: To assess the possible cerebral haemodynamic changes occurring in preterm infants after blood transfusions. Methods: Preterm infants who had undergone blood transfusions were prospectively studied using both near infrared spectroscopy and cerebral Doppler ultrasonography. Results: Fourteen infants (mean gestational age 29.6 wk, SD 2.6; mean birthweight 1430 g, SD 332) were studied at the mean age of 29 (SD 14) d. A significant increase in oxygenated haemoglobin (O(2)Hb), deoxygenated haemoglobin (HHb), mixed cerebral oxygen saturation (SmO2) and change in cerebral blood volume occurred after transfusion. Between ultrasound parameters, we found a decrease in diastolic velocity and an increase in resistance index. Conclusion: Blood transfusions improve cerebral oxygen supply and induce a decrease in cerebral blood volume, probably due to an increase in cerebral vessel resistance.

引用

页码：938 / 941

页数：4

共 17 条

[1] Brain hemodynamic changes in preterm infants after maintenance dose caffeine and aminophylline treatment [J].

Dani, C ;

Bertini, G ;

Reali, MF ;

Tronchin, M ;

Wiechmann, L ;

Martelli, E ;

Rubaltelli, FF .

BIOLOGY OF THE NEONATE, 2000, 78 (01) :27-32

[2] QUANTIFICATION OF CONCENTRATION CHANGES IN NEONATAL HUMAN CEREBRAL OXIDIZED CYTOCHROME-OXIDASE [J].

EDWARDS, AD ;

BROWN, GC ;

COPE, M ;

WYATT, JS ;

MCCORMICK, DC ;

ROTH, SC ;

DELPY, DT ;

REYNOLDS, EOR .

JOURNAL OF APPLIED PHYSIOLOGY, 1991, 71 (05) :1907-1913

[3]

JONES MD, 1984, SEMIN PERINATOL, V8, P205

[4] The effect of blood transfusion and haemodilution on cerebral oxygenation and haemodynamics in newborn infants investigated by near infrared spectrophotometry [J].

Liem, KD ;

Hopman, JCW ;

Oeseburg, B ;

deHaan, AFJ ;

Kollee, LAA .

EUROPEAN JOURNAL OF PEDIATRICS, 1997, 156 (04) :305-310

[5]

Lipp-Zwahlen A E, 1989, Acta Paediatr Scand Suppl, V360, P26

[6] INTRAVENOUS AMINOPHYLLINE AND CEREBRAL BLOOD-FLOW IN PRETERM INFANTS [J].

MCDONNELL, M ;

IVES, NK ;

HOPE, PL .

ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 1992, 67 (04) :416-418

[7] EFFECTS OF RED-CELL TRANSFUSION ON CARDIAC-OUTPUT AND BLOOD-FLOW VELOCITIES IN CEREBRAL AND GASTROINTESTINAL ARTERIES IN PREMATURE-INFANTS [J].

NELLE, M ;

HOCKER, C ;

ZILOW, EP ;

LINDERKAMP, O .

ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 1994, 71 (01) :F45-F48

[8] BLOOD-SAMPLING IN VERY LOW BIRTH-WEIGHT INFANTS RECEIVING DIFFERENT LEVELS OF INTENSIVE-CARE [J].

OBLADEN, M ;

SACHSENWEGER, M ;

STAHNKE, M .

EUROPEAN JOURNAL OF PEDIATRICS, 1988, 147 (04) :399-404

[9] INCIDENCE AND EVOLUTION OF SUBEPENDYMAL AND INTRA-VENTRICULAR HEMORRHAGE - STUDY OF INFANTS WITH BIRTH WEIGHTS LESS THAN 1,500 GM [J].

PAPILE, LA ;

BURSTEIN, J ;

BURSTEIN, R ;

KOFFLER, H .

JOURNAL OF PEDIATRICS, 1978, 92 (04) :529-534

[10]

PERLMAN JM, 1998, FETAL NEONATAL PHYSL, P2175

← 1 2 →