From Discovery to Practice and Survivorship: Building a National Real-World Data Learning Healthcare Framework for Military and Veteran Cancer Patients

被引：18

作者：

Lee, Jerry S. H. ^{[1
,2
,3
,4
,5
,6
]}

Darcy, Kathleen M. ^{[4
,7
,8
,9
]}

Hu, Hai ^{[10
]}

Casablanca, Yovanni ^{[7
,8
,9
]}

Conrads, Thomas P. ^{[11
]}

Dalgard, Clifton L. ^{[12
,13
]}

Freymann, John B. ^{[14
]}

Hanlon, Sean E. ^{[5
]}

Huang, Grant D. ^{[6
]}

Kvecher, Leonid ^{[10
]}

Maxwell, George L. ^{[11
]}

Meng, Frank ^{[15
,16
]}

Moncur, Joel T. ^{[17
]}

Turner, Clesson ^{[18
]}

Wells, Justin M. ^{[19
]}

Wilkerson, Matthew D. ^{[4
,12
,13
]}

Zhu, Kangmin ^{[8
,9
]}

Ramoni, Rachel B. ^{[6
]}

Shriver, Craig D. ^{[8
,9
,20
]}

机构：

[1] Univ Southern Calif, Keck Sch Med, Dept Med Oncol, Los Angeles, CA 90033 USA

[2] Univ Southern Calif, Viterbi Sch Engn, Dept Chem Engn & Mat Sci, Los Angeles, CA 90033 USA

[3] Univ Southern Calif, Lawrence J Ellison Inst Transformat Med, Los Angeles, CA 90033 USA

[4] Henry M Jackson Fdn Adv Mil Med, Bethesda, MD 20817 USA

[5] NCI, Ctr Strateg Sci Initiat, Bethesda, MD 20892 USA

[6] US Dept Vet Affairs, Off Res & Dev, Washington, DC 20421 USA

[7] Uniformed Serv Univ Hlth Sci, Dept Obstet & Gynecol, Gynecol Canc Ctr Excellence, Bethesda, MD 20814 USA

[8] Walter Reed Natl Mil Med Ctr, Bethesda, MD USA

[9] Uniformed Serv Univ Hlth Sci, John P Murtha Canc Ctr, Res Program, Dept Surg, Bethesda, MD 20814 USA

[10] Chan Soon Shiong Inst Mol Med Windber, Windber, PA USA

[11] Inova Fairfax Hosp, Inova Schar Canc Inst, Dept Obstet & Gynecol, Falls Church, VA USA

[12] Uniformed Serv Univ Hlth Sci, Dept Anat Physiol & Genet, Bethesda, MD 20814 USA

[13] Uniformed Serv Univ Hlth Sci, Amer Genome Ctr, Collaborat Hlth Initiat Res Program, Bethesda, MD 20814 USA

[14] Frederick Natl Lab Canc Res, Leidos Biomed Res Inc, Canc Imaging Informat Lab, Frederick, MD USA

[15] Vet Affairs Boston Healthcare, Massachusetts Vet Epidemiol Res & Informat Ctr, Boston, MA USA

[16] Boston Univ, Sch Med, Dept Gen Internal Med, Boston, MA 02118 USA

[17] Def Hlth Agcy, Joint Pathol Ctr, Natl Capital Reg Med Directorate, Silver Spring, MD USA

[18] Walter Reed Natl Mil Med Ctr, Div Genet, Dept Pediat, Bethesda, MD USA

[19] Walter Reed Natl Mil Med Ctr, Dept Pathol, Bethesda, MD USA

[20] Uniformed Serv Univ Hlth Sci, Dept Surg, Bethesda, MD 20814 USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2019年 / 106卷 / 01期

基金：

美国国家卫生研究院;

关键词：

SURVIVAL;

D O I：

10.1002/cpt.1425

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The Applied Proteogenomics OrganizationaL Learning and Outcomes (APOLLO) network is implementing a prospective curation and translation of real-world data (RWD) into real-world evidence (RWE) within the learning healthcare environment of the Department of Defense and Department of Veterans Affairs. To support basic, translational, clinical, and epidemiological sciences, APOLLO will release data to public repositories for secondary analysis to assist others in assessing whether similar molecular-driven clinical practice guidelines will improve health outcomes for their relevant cancer populations.

引用

页码：52 / 57

页数：6

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