Germ cell cancer risk in DSD patients

被引：13

作者：

Cools, Martine ^{[1
]}

机构：

[1] Univ Ghent, Dept Pediat & Genet, Ghent Univ Hosp, B-9000 Ghent, Belgium

来源：

ANNALES D ENDOCRINOLOGIE | 2014年 / 75卷 / 02期

关键词：

DSD; Germ cell tumor; Risk; Gonadectomy; ANDROGEN INSENSITIVITY SYNDROME; SEX DEVELOPMENT DSD; CARCINOMA IN-SITU; GENOME-WIDE ASSOCIATION; TESTICULAR CANCER; DYSGENETIC GONADS; FOLLOW-UP; TUMORS; DISORDERS; MEN;

D O I：

10.1016/j.ando.2014.04.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The risk of germ cell cancer is elevated in many DSD patients, although not to the same extent. A number of risk factors have been recently, but their interplay and relative impact is currently not fully clear. Until the advent of reliable screening tools for the detection of cancer lesions, managing germ cell tumour risk focuses on the question if and when to perform biopsy or gonadectomy in most patients and to interpret the histological findings. (C) 2014 Elsevier Masson SAS. All rights reserved.

引用

页码：67 / 71

页数：5

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