DNA damage responses in central nervous system and age-associated neurodegeneration

被引:10
作者
Hegde, Muralidhar L. [1 ,2 ,3 ]
Bohr, Vilhelm A. [4 ]
Mitra, Sankar [1 ,3 ]
机构
[1] Houston Methodist Res Inst, Dept Radiat Oncol, Houston, TX 77030 USA
[2] Houston Methodist Neurol Inst, Houston, TX 77030 USA
[3] Cornell Univ, Weill Med Coll, New York, NY 10021 USA
[4] NIA, Lab Mol Gerontol, NIH, Baltimore, MD 21224 USA
关键词
STRAND BREAK REPAIR; ATAXIA-TELANGIECTASIA; ALZHEIMERS-DISEASE; COCKAYNE-SYNDROME; EXCISION-REPAIR; BRAIN; INSTABILITY; DEFICIENCY; INTEGRITY; MUTATION;
D O I
10.1016/j.mad.2017.01.010
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:1 / 3
页数:3
相关论文
共 25 条
[11]   Age-Related Neuronal Degeneration: Complementary Roles of Nucleotide Excision Repair and Transcription-Coupled Repair in Preventing Neuropathology [J].
Jaarsma, Dick ;
van der Pluijm, Ingrid ;
de Waard, Monique C. ;
Haasdijk, Elize D. ;
Brandt, Renata ;
Vermeij, Marcel ;
Rijksen, Yvonne ;
Maas, Alex ;
van Steeg, Harry ;
Hoeijmakers, Jan H. J. ;
van der Horst, Gijsbertus T. J. .
PLOS GENETICS, 2011, 7 (12)
[12]   INSTABILITY AND DECAY OF THE PRIMARY STRUCTURE OF DNA [J].
LINDAHL, T .
NATURE, 1993, 362 (6422) :709-715
[13]   Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice [J].
Manley, K ;
Shirley, TL ;
Flaherty, L ;
Messer, A .
NATURE GENETICS, 1999, 23 (04) :471-473
[14]   An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele [J].
Maser, RS ;
Zinkel, R ;
Petrini, JHJ .
NATURE GENETICS, 2001, 27 (04) :417-421
[15]   DNA repair deficiency and neurological disease [J].
McKinnon, Peter J. .
NATURE REVIEWS NEUROSCIENCE, 2009, 10 (02) :100-112
[16]   ATM and ataxia telangiectasia - Second in Molecular Medicine Review Series [J].
McKinnon, PJ .
EMBO REPORTS, 2004, 5 (08) :772-776
[17]   A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis [J].
Niedernhofer, Laura J. ;
Garinis, George A. ;
Raams, Anja ;
Lalai, Astrid S. ;
Robinson, Andria Rasile ;
Appeldoorn, Esther ;
Odijk, Hanny ;
Oostendorp, Roos ;
Ahmad, Anwaar ;
Van Leeuwen, Wibeke ;
Theil, Arjan F. ;
Vermeulen, Wim ;
van der Horst, Gijsbertus T. J. ;
Meinecke, Peter ;
Kleijer, Wim J. ;
Vijg, Jan ;
Jaspers, Nicolaas G. J. ;
Hoeijmakers, Jan H. J. .
NATURE, 2006, 444 (7122) :1038-1043
[18]   DNA end joining activity is reduced in Alzheimer's disease [J].
Shackelford, DA .
NEUROBIOLOGY OF AGING, 2006, 27 (04) :596-605
[19]   Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β [J].
Suberbielle, Elsa ;
Sanchez, Pascal E. ;
Kravitz, Alexxai V. ;
Wang, Xin ;
Ho, Kaitlyn ;
Eilertson, Kirsten ;
Devidze, Nino ;
Kreitzer, Anatol C. ;
Mucke, Lennart .
NATURE NEUROSCIENCE, 2013, 16 (05) :613-+
[20]   Maintaining genetic integrity in aging: A zero sum game [J].
Suh, Yousin ;
Vijg, Jan .
ANTIOXIDANTS & REDOX SIGNALING, 2006, 8 (3-4) :559-571