An unusual cause of food-induced anaphylaxis in mothers

被引：9

作者：

Soh, J. Y. ^{[1
,2
]}

Chiang, W. C. ^{[3
]}

Huang, C. H. ^{[1
,2
]}

Woo, C. K. ^{[4
]}

Ibrahim, I. ^{[5
,6
]}

Heng, K. ^{[6
,7
]}

Pramanick, A. ^{[8
]}

Lee, B. W. ^{[1
,2
]}

机构：

[1] Natl Univ Singapore Hosp, Dept Paediat, Tower Block Level 12,1E Kent Ridge Rd, Singapore 119228, Singapore

[2] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Paediat, Singapore, Singapore

[3] Kandang Kerbau Womens & Childrens Hosp, Dept Paediat, Singapore, Singapore

[4] Gleneagles Hosp Kuala Lumpur, Dept Med, Kuala Lumpur, Malaysia

[5] Natl Univ Hlth Syst, Natl Univ Hosp, Emergency Med Dept, Singapore, Singapore

[6] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Surg, Singapore, Singapore

[7] Tan Tock Seng Hosp, Emergency Dept, Singapore, Singapore

[8] Kandang Kerbau Womens & Childrens Hosp, Dept Obstet & Gynaecol, Singapore, Singapore

来源：

WORLD ALLERGY ORGANIZATION JOURNAL | 2017年 / 10卷

基金：

英国医学研究理事会;

关键词：

Anaphylaxis; Pregnancy; Galacto-Oligosaccharide; ALPHA-GAL; NONDIGESTIBLE OLIGOSACCHARIDES; PREGNANCY; FRUCTOOLIGOSACCHARIDE; SUPPLEMENTATION; SENSITIZATION; FORMULA; ALLERGY; MICE; TERM;

D O I：

10.1186/s40413-016-0136-x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Background: Galacto-oligosaccharides (GOS) are prebiotics added to commercial milk formula of infants and mothers. In recent years, cases of allergy related to GOS in atopic children have been reported in the South East Asian region. Case presentations: We describe a series of pregnant (n = 4) and lactating mothers (n = 2) who developed anaphylactic reactions after consumption of maternal milk formula containing GOS. All six subjects had preexisting atopy and a positive skin prick test to GOS and 5/5 of the subjects who were tested had positive basophil activation tests to GOS. All of the mothers and their babies had normal neonatal outcomes after the reactions. Conclusions: The supplementation of GOS into milk and beverages in the Asian region should take into account the rare chance of allergenicity of GOS in the atopic population.

引用

页数：5

共 29 条

[1] Allergic airway diseases in a tropical urban environment are driven by dominant mono-specific sensitization against house dust mites
Andiappan, A. K.
Puan, K. J.
Lee, B.
Nardin, A.
Poidinger, M.
Connolly, J.
Chew, F. T.
Wang, D. Y.
Rotzschke, O.
[J]. ALLERGY, 2014, 69 (04) : 501 - 509
[2] Berenguer A, 2013, BMJ CASE REP, DOI [10.1136/bcr-2012-07055, DOI 10.1136/BCR-2012-07055]
[3] Antibiotics at term. Questions about five severe allergic accidents
Berthier, A.
Sentilhes, L.
Hamou, L.
Renoult-Litzler, D.
Marret, S.
Marpeau, L.
[J]. GYNECOLOGIE OBSTETRIQUE & FERTILITE, 2007, 35 (05): : 464 - 472
[4] Calamari AM, 2015, EUR ANN ALLERGY CLIN, V47, P161
[5] Anaphylactic shock in pregnancy: a case study and review of the literature
Chaudhuri, K.
Gonzales, J.
Jesurun, C. A.
Ambat, M. T.
Mandal-Chaudhuri, S.
[J]. INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA, 2008, 17 (04) : 350 - 357
[6] Anaphylaxis to cow's milk formula containing short-chain galacto-oligosaccharide
Chiang, Wen Chin
Huang, Chiung-Hui
Llanora, Genevieve V.
Gerez, Irvin
Goh, Si Hui
Shek, Lynette P. C.
Nauta, Alma J.
Van Doorn, Wilhelmina A.
Bindels, Jacques
Ulfman, Laurien H.
Knipping, Karen
Delsing, Dianne J.
Knol, Edward F.
Lee, Bee Wah
[J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2012, 130 (06) : 1361 - 1367
[7] Haemaphysalis longicornis tick bites are a possible cause of red meat allergy in Japan
Chinuki, Y.
Ishiwata, K.
Yamaji, K.
Takahashi, H.
Morita, E.
[J]. ALLERGY, 2016, 71 (03) : 421 - 425
[8] Delayed anaphylaxis to alpha-gal, an oligosaccharide in mammalian meat
Commins, Scott P.
Jerath, Maya R.
Cox, Kelly
Erickson, Loren D.
Platts-Mills, Thomas
[J]. ALLERGOLOGY INTERNATIONAL, 2016, 65 (01) : 16 - 20
[9] In-Depth Characterization of Prebiotic Galacto-oligosaccharides by a Combination of Analytical Techniques
Coulier, Leon
Timmermans, Johan
Bas, Richard
Van Den Dool, Ron
Haaksman, Ingrid
Klarenbeck, Bert
Slaghek, Ted
Van Dongen, William
[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009, 57 (18) : 8488 - 8495
[10] ANAPHYLAXIS IN PREGNANCY
ENTMAN, SS
MOISE, KJ
[J]. SOUTHERN MEDICAL JOURNAL, 1984, 77 (03) : 402 - 403

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