Treatment Responses in Antiretroviral Treatment-Naive Premenopausal and Postmenopausal HIV-1-Infected Women: An Analysis from AIDS Clinical Trials Group Studies

被引：18

作者：

Patterson, Kristine B. ^{[1
]}

Cohn, Susan E. ^{[2
]}

Uyanik, Jennifer ^{[3
]}

Hughes, Michael ^{[3
]}

Smurzynski, Marlene ^{[3
]}

Eron, Joseph J.

机构：

[1] Univ N Carolina, Sch Med, Div Infect Dis, Chapel Hill, NC 27599 USA

[2] Univ Rochester, Rochester, NY USA

[3] Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2009年 / 49卷 / 03期

关键词：

HUMAN-IMMUNODEFICIENCY-VIRUS; CD4 CELL COUNTS; INITIAL TREATMENT; HIV-1; INFECTION; RNA LEVELS; REGIMENS; OLDER; AGE; SEX; THERAPY;

D O I：

10.1086/600398

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Menopause may affect antiretroviral treatment (ART) response. Immunologic and virologic responses to ART were compared in 220 premenopausal and 47 postmenopausal women enrolled in 2 studies involving ART-naive persons. Changes in CD4 counts or human immunodeficiency virus type 1 RNA levels were similar at 24, 48, and 96 weeks after treatment initiation. ART-naive women should respond to ART regardless of menopausal status.

引用

页码：473 / 476

页数：4

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