Molecular mimicry as a mechanism for the uptake of cysteine S-conjugates of methylmercury and inorganic mercury

被引：10
作者：
Bridges, Christy C. [1 ]
Zalups, Rudolfs K. [1 ]
机构：
[1] Mercer Univ, Sch Med, Div Basic Med Sci, Macon, GA 31207 USA
来源：
CHEMICAL RESEARCH IN TOXICOLOGY | 2006年 / 19卷 / 09期
关键词：
D O I：
10.1021/tx060158i
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：1117 / 1118
页数：2
相关论文
共 18 条
[1]   METHYLMERCURY UPTAKE IN RAT PRIMARY ASTROCYTE CULTURES - THE ROLE OF THE NEUTRAL AMINO-ACID-TRANSPORT SYSTEM [J].
ASCHNER, M ;
EBERLE, NB ;
GODERIE, S ;
KIMELBERG, HK .
BRAIN RESEARCH, 1990, 521 (1-2) :221-228
[2]   METHYL MERCURY UPTAKE ACROSS BOVINE BRAIN CAPILLARY ENDOTHELIAL-CELLS INVITRO - THE ROLE OF AMINO-ACIDS [J].
ASCHNER, M ;
CLARKSON, TW .
PHARMACOLOGY & TOXICOLOGY, 1989, 64 (03) :293-299
[3]   UPTAKE OF METHYLMERCURY IN THE RAT-BRAIN - EFFECTS OF AMINO-ACIDS [J].
ASCHNER, M ;
CLARKSON, TW .
BRAIN RESEARCH, 1988, 462 (01) :31-39
[4]  
ASHNER M, 1989, PHARMACOL TOXICOL, V65, P17
[5]   Molecular and ionic mimicry and the transport of toxic metals [J].
Bridges, CC ;
Zalups, RK .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2005, 204 (03) :274-308
[6]   Mercuric conjugates of cysteine are transported by the amino acid transporter system b0,+:: Implications of molecular mimicry [J].
Bridges, CC ;
Bauch, C ;
Verrey, F ;
Zalups, RK .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2004, 15 (03) :663-673
[7]  
Cannon VT, 2000, J AM SOC NEPHROL, V11, P394, DOI 10.1681/ASN.V113394
[8]  
Cannon VT, 2001, J PHARMACOL EXP THER, V298, P780
[9]  
Clarkson T. W., 1993, ANN REV PHARM TOXICO, P545
[10]   METHYLMERCURY TRANSPORT ACROSS THE BLOOD-BRAIN-BARRIER BY AN AMINO-ACID CARRIER [J].
KERPER, LE ;
BALLATORI, N ;
CLARKSON, TW .
AMERICAN JOURNAL OF PHYSIOLOGY, 1992, 262 (05) :R761-R765
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