Production of resveratrol in recombinant microorganisms

被引：147

作者：

Beekwilder, Jules ^{[1
]}

Wolswinkel, Rianne ^{[1
]}

Jonker, Harry ^{[1
]}

Hall, Robert ^{[1
]}

Ric de Vos, C. H. ^{[1
]}

Bovy, Arnaud ^{[1
]}

机构：

[1] Plant Res Int, NL-6700 AA Wageningen, Netherlands

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2006年 / 72卷 / 08期

关键词：

D O I：

10.1128/AEM.00609-06

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Resveratrol production in Saccharomyces cerevisiae was compared to that in Escherichia coli. In both systems, 4-coumarate:coenzyme A ligase from tobacco and stilbene synthase from grapes were expressed. When p-coumaric acid was used as the precursor, resveratrol accumulations in the culture medium were observed to be comparable in E. coli (16 mg/liter) and yeast (6 mg/liter).

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页码：5670 / 5672

页数：3

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