One of These is Not Like the Others

被引：1
作者：
Pavelka, Martin S., Jr. [1 ]
机构：
[1] Univ Rochester, Med Ctr, Dept Microbiol & Immunol, Rochester, NY 14642 USA
来源：
TRENDS IN MICROBIOLOGY | 2015年 / 23卷 / 11期
关键词：
MYCOBACTERIUM-TUBERCULOSIS; AUXOTROPH; PROTECTION; LYSINE;
D O I：
10.1016/j.tim.2015.09.005
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A Mycobacterium tuberculosis metA mutant that is auxotrophic for methionine is unlike other auxotrophic mutants of this important species as methionine starvation results in rapid death instead of cessation of growth. Evidence suggests that this phenotype results from starvation affecting essential pathways that utilize Sadenosylmethionine in addition to methionine.
引用
收藏
页码：668 / 670
页数：3
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