Intracellular Zn2+ detection with quantum dot-based FLIM nanosensors

被引：16
|
作者：
Ripoll, Consuelo [1 ]
Martin, Miguel [2 ]
Roldan, Mar [2 ]
Talavera, Eva M. [1 ]
Orte, Angel [1 ]
Ruedas-Rama, Maria J. [1 ]
机构：
[1] Univ Granada, Fac Pharm, Dept Phys Chem, E-18071 Granada, Spain
[2] Pfizer Univ Granada Junta Andalucia Ctr Genom & O, GENYO, Granada 18016, Spain
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 95期
关键词：
LIFETIME IMAGING MICROSCOPY; FLUORESCENT SENSOR; ZINC; PH; CELLS; INDICATORS;
D O I：
10.1039/c5cc06676j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Fluorescence Lifetime Imaging Microscopy (FLIM) has been employed for the detection of intracellular Zn2+ levels, implicated in various signalling pathways, using a family of quantum dot (QD) nanosensors. The sensing mechanism was based on photoinduced electron transfer (PET) between an azacycle receptor group and the QD nanoparticles.
引用
收藏
页码：16964 / 16967
页数：4
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