Intracellular Zn2+ detection with quantum dot-based FLIM nanosensors

被引:16
|
作者
Ripoll, Consuelo [1 ]
Martin, Miguel [2 ]
Roldan, Mar [2 ]
Talavera, Eva M. [1 ]
Orte, Angel [1 ]
Ruedas-Rama, Maria J. [1 ]
机构
[1] Univ Granada, Fac Pharm, Dept Phys Chem, E-18071 Granada, Spain
[2] Pfizer Univ Granada Junta Andalucia Ctr Genom & O, GENYO, Granada 18016, Spain
关键词
LIFETIME IMAGING MICROSCOPY; FLUORESCENT SENSOR; ZINC; PH; CELLS; INDICATORS;
D O I
10.1039/c5cc06676j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Fluorescence Lifetime Imaging Microscopy (FLIM) has been employed for the detection of intracellular Zn2+ levels, implicated in various signalling pathways, using a family of quantum dot (QD) nanosensors. The sensing mechanism was based on photoinduced electron transfer (PET) between an azacycle receptor group and the QD nanoparticles.
引用
收藏
页码:16964 / 16967
页数:4
相关论文
共 50 条
  • [1] A Quantum Dot-Based FLIM Glucose Nanosensor
    Ripoll, Consuelo
    Orte, Angel
    Paniza, Lorena
    Jose Ruedas-Rama, Maria
    SENSORS, 2019, 19 (22)
  • [2] A novel carboxymethyl chitosan-quantum dot-based intracellular probe for Zn2+ ion sensing in prostate cancer cells
    Ma, Qiang
    Lin, Zi-Han
    Yang, Na
    Li, Yang
    Su, Xing-Guang
    ACTA BIOMATERIALIA, 2014, 10 (02) : 868 - 874
  • [3] Quantum Dot-Based Molecular Beacon to Monitor Intracellular MicroRNAs
    Lee, Jonghwan
    Moon, Sung Ung
    Lee, Yong Seung
    Ali, Bahy A.
    Al-Khedhairy, Abdulaziz A.
    Ali, Daoud
    Ahmed, Javed
    Al Salem, Abdullah M.
    Kim, Soonhag
    SENSORS, 2015, 15 (06) : 12872 - 12883
  • [4] Carbon-Dot-Based Nanosensors for the Detection of Intracellular Redox State
    Liu, Ye
    Tian, Ye
    Tian, Yefei
    Wang, Yajun
    Yang, Wuli
    ADVANCED MATERIALS, 2015, 27 (44) : 7156 - +
  • [5] Graphene quantum dot based "switch-on" nanosensors for intracellular cytokine monitoring
    Liu, Guozhen
    Zhang, Kai
    Ma, Ke
    Care, Andrew
    Hutchinson, Mark R.
    Goldys, Ewa M.
    NANOSCALE, 2017, 9 (15) : 4934 - 4943
  • [6] Quantum Dot-Based Hybrid Coacervate Nanodroplets for Ultrasensitive Detection of Hg2+
    Singh, Shivendra
    Vaishnav, Jamuna K.
    Mukherjee, Tushar Kanti
    ACS APPLIED NANO MATERIALS, 2020, 3 (04) : 3604 - 3612
  • [7] Increase in intracellular Zn2+ concentration by thimerosal in rat thymocytes: Intracellular Zn2+ release induced by oxidative stress
    Hashimoto, Erika
    Oyama, Toshihisa B.
    Oyama, Keisuke
    Nishimura, Yumiko
    Oyama, Tomohiro M.
    Ueha-Ishibashi, Toshiko
    Okano, Yoshiro
    Oyama, Yasuo
    TOXICOLOGY IN VITRO, 2009, 23 (06) : 1092 - 1099
  • [8] Zn(II)-Coordinated Quantum Dot-FRET Nanosensors for the Detection of Protein Kinase Activity
    Lim, Butaek
    Park, Ji-In
    Lee, Kyung Jin
    Lee, Jin-Won
    Kim, Tae-Wuk
    Kim, Young-Pil
    SENSORS, 2015, 15 (08): : 17977 - 17989
  • [9] An imidazole derivative-based chemodosimeter for Zn2+ and Cu2+ ions through "ON-OFF-ON" switching with intracellular Zn2+ detection
    Ansari, Shagufi N.
    Saini, Anoop K.
    Kumari, Pratibha
    Mobin, Shaikh M.
    INORGANIC CHEMISTRY FRONTIERS, 2019, 6 (03) : 736 - 745
  • [10] A quantum dot-based ratiometric pH sensor
    Jin, Takashi
    Sasaki, Akira
    Kinjo, Masataka
    Miyazaki, Jun
    CHEMICAL COMMUNICATIONS, 2010, 46 (14) : 2408 - 2410