Nutritional components regulate the gut immune system and its association with intestinal immune disease development

被引：15
|
作者：
Lamichhane, Aayam [1 ,2 ,4 ,5 ]
Kiyono, Hiroshi [1 ,2 ,3 ,4 ]
Kunisawa, Jun [1 ,2 ,3 ,5 ,6 ]
机构：
[1] Univ Tokyo, Inst Med Sci, Dept Microbiol & Immunol, Div Mucosal Immunol, Tokyo, Japan
[2] Japan Sci & Technol Agcy, CREST, Tokyo, Japan
[3] Univ Tokyo, Inst Med Sci, Int Res & Dev Ctr Mucosal Vaccines, Tokyo, Japan
[4] Univ Tokyo, Grad Sch Frontier Sci, Dept Med Genome Sci, Chiba, Japan
[5] Osaka Univ, Natl Inst Biomed Innovat, Lab Vaccine Mat, Osaka, Japan
[6] Osaka Univ, Grad Sch Pharmaceut Sci, Osaka, Japan
来源：
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | 2013年 / 28卷
关键词：
allergy; intestinal immunity; lipid; nucleotide; vitamin; SPHINGOSINE; 1-PHOSPHATE; LYMPHOCYTE EGRESS; DENDRITIC CELLS; T-CELLS; B-CELLS; TRAFFICKING; FTY720; INFLAMMATION; FOLATE; TH2;
D O I：
10.1111/jgh.12259
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
The gut is equipped with a unique immune system for maintaining immunological homeostasis, and its functional immune disruption can result in the development of immune diseases such as food allergy and intestinal inflammation. Accumulating evidence has demonstrated that nutritional components play an important role in the regulation of gut immune responses and also in the development of intestinal immune diseases. In this review, we focus on the immunological functions of lipids, vitamins, and nucleotides in the regulation of the intestinal immune system and as potential targets for the control of intestinal immune diseases.
引用
收藏
页码：18 / 24
页数：7
相关论文
共 50 条
  • [41] Does the microbiota regulate immune responses outside the gut?
    Noverr, MC
    Huffnagel, GB
    TRENDS IN MICROBIOLOGY, 2004, 12 (12) : 562 - 568
  • [42] Nutrition and the immune system of the gut
    Cunningham-Rundles, S
    Lin, DH
    NUTRITION, 1998, 14 (7-8) : 573 - 579
  • [43] Gut immune cells and intestinal niche imprinting
    Rivera, Claudia A.
    Lennon-Dumenil, Ana-Maria
    SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2023, 150 : 50 - 57
  • [44] Pharmacological Modulation of Immune Responses by Nutritional Components
    van Daal, Marthe T.
    Folkerts, Gert
    Garssen, Johan
    Braber, Saskia
    PHARMACOLOGICAL REVIEWS, 2021, 73 (04) : 198 - 232
  • [45] Immune-mediated Bowel Disease: Role of Intestinal Parasites and Gut Microbiome
    Chowdhury, Sejuti Ray
    Dey, Arup
    Gautam, Manish Kumar
    Mondal, Sandip
    Pawar, Sharad D.
    Ranade, Anagha
    Bora, Manajit
    Gangwar, Mayank
    Teli, Aniya
    Mondal, Nur Shaid
    CURRENT PHARMACEUTICAL DESIGN, 2024, 30 (40) : 3164 - 3174
  • [46] Erratum: The gut microbiota shapes intestinal immune responses during health and disease
    June L. Round
    Sarkis K. Mazmanian
    Nature Reviews Immunology, 2009, 9 : 600 - 600
  • [47] Gut Dysbiosis and Immune System in Atherosclerotic Cardiovascular Disease (ACVD)
    Yoo, Ji Youn
    Sniffen, Sarah
    McGill Percy, Kyle Craig
    Pallaval, Veera Bramhachari
    Chidipi, Bojjibabu
    MICROORGANISMS, 2022, 10 (01)
  • [48] Immunodeficiency and the gut: clues to the role of the immune system in gastrointestinal disease
    Klein, N
    Jack, D
    ITALIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 1999, 31 (08): : 802 - 806
  • [49] GUT MICROBIOTA AND THE IMMUNE SYSTEM: AN INTIMATE PARTNERSHIP IN HEALTH AND DISEASE
    Iebba, V.
    Nicoletti, M.
    Schippa, S.
    INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY, 2012, 25 (04) : 823 - 833
  • [50] The trajectory of immune development in early life and its association with clinical allergic disease outcomes
    Gamez, C.
    Leffler, J.
    Prescott, S. L.
    Strickland, D.
    Palmer, D. J.
    Rueter, K.
    ALLERGY, 2021, 76 : 18 - 18
12345