Environment-friendly Synthesis of Bioactive Pyrazoles

被引：36

作者：

Pizzuti, Lucas ^{[1
]}

Barschak, Alethea G. ^{[2
]}

Stefanello, Francieli M. ^{[2
]}

Farias, Marilia D. ^{[2
]}

Lencina, Claiton ^{[2
]}

Roesch-Ely, Mariana ^{[3
]}

Cunico, Wilson ^{[2
]}

Moura, Sidnei ^{[3
]}

Pereira, Claudio M. P. ^{[2
]}

机构：

[1] Fundacao Univ Fed Grande Dourados, Fac Ciencias Exatas & Tecnol, BR-79825070 Dourados, RS, Brazil

[2] Univ Fed Pelotas, Ctr Ciencias Quim Farmaceut & Alimentos, BR-96010900 Capao Do Leao Pelotas, RS, Brazil

[3] Univ Caxias Sul, Inst Biotecnol, BR-95070560 Caxias Do Sul, RS, Brazil

来源：

CURRENT ORGANIC CHEMISTRY | 2014年 / 18卷 / 01期

关键词：

Pyrazoles; green synthesis; bioactivity; MICROWAVE-ASSISTED SYNTHESIS; LIVER ALCOHOL-DEHYDROGENASE; BIOLOGICAL EVALUATION; ANTIMICROBIAL ACTIVITY; GREEN CHEMISTRY; MULTICOMPONENT SYNTHESIS; FLUORINATED ALCOHOLS; ANTITUMOR-ACTIVITY; ANTIVIRAL ACTIVITY; POTENTIAL AGENTS;

D O I：

10.2174/13852728113179990029

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyrazoles are compounds of synthetic origin, and constitute a group of nitrogen heterocyclic compounds that have shown several biological activities. Their transformations into other biologically active molecules have been exploited since the early 1960s. This review describes the work on the environment-friendly synthesis of bioactive pyrazoles. The review covers mainly the data published over the last five years (2007-2012).

引用

页码：115 / 126

页数：12

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