Antisense oligonucleotide therapy for splicing defects in OPA1-related dominant optic atrophy

被引：0
作者：
Wissinger, B. [1 ]
Synofzik, M. [2 ]
Schols, L. [2 ]
Bonifert, T. [1 ]
机构：
[1] Univ Tubingen, Ctr Ophthalmol, Tubingen, Germany
[2] Univ Tubingen, Dept Neurodegenerat Dis, Hertie Inst Clin Brain Res, Tubingen, Germany
来源：
ACTA OPHTHALMOLOGICA | 2017年 / 95卷
关键词：
D O I：
10.1111/j.1755-3768.2017.03173
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
引用
收藏
页数：1
相关论文
共 50 条
  • [31] Omega-3 fatty acids promote neuroprotection, decreased apoptosis and reduced glial cell activation in the retina of a mouse model of OPA1-related autosomal dominant optic atrophy
    Kalogerou, Maria
    Ioannou, Sotiris
    Kolovos, Panagiotis
    Prokopiou, Ekatherine
    Potamiti, Louiza
    Kyriacou, Kyriacos
    Panagiotidis, Michail
    Ioannou, Maria
    Fella, Eleni
    Worth, Elena Panayiotou
    Georgiou, Tassos
    EXPERIMENTAL EYE RESEARCH, 2022, 215
  • [32] Spectrum, frequency and penetrance of OPA1 mutations in dominant optic atrophy
    Toomes, C
    Marchbank, NJ
    Mackey, DA
    Craig, JE
    Newbury-Ecob, RA
    Bennett, CP
    Vize, CJ
    Desai, SP
    Black, GCM
    Patel, N
    Teimory, M
    Markham, AF
    Inglehearn, CF
    Churchill, AJ
    HUMAN MOLECULAR GENETICS, 2001, 10 (13) : 1369 - 1378
  • [33] Heterozygous deletion of the OPA1 gene in patients with dominant optic atrophy
    Hayashi, Takaaki
    Sasano, Hiroyuki
    Katagiri, Satoshi
    Tsunoda, Kazushige
    Kameya, Shuhei
    Nakazawa, Mitsuru
    Iwata, Takeshi
    Tsuneoka, Hiroshi
    JAPANESE JOURNAL OF OPHTHALMOLOGY, 2017, 61 (05) : 395 - 401
  • [34] Idebenone treatment in patients with OPA1-mutant dominant optic atrophy
    Barboni, Piero
    Valentino, Maria Lucia
    La Morgia, Chiara
    Carbonelli, Michele
    Savini, Giacomo
    De Negri, Annamaria
    Simonelli, Francesca
    Sadun, Federico
    Caporali, Leonardo
    Maresca, Alessandra
    Liguori, Rocco
    Baruzzi, Agostino
    Zeviani, Massimo
    Carelli, Valerio
    BRAIN, 2013, 136
  • [35] Heterozygous deletion of the OPA1 gene in patients with dominant optic atrophy
    Takaaki Hayashi
    Hiroyuki Sasano
    Satoshi Katagiri
    Kazushige Tsunoda
    Shuhei Kameya
    Mitsuru Nakazawa
    Takeshi Iwata
    Hiroshi Tsuneoka
    Japanese Journal of Ophthalmology, 2017, 61 : 395 - 401
  • [36] The genetic landscape for isolated not-OPA1 autosomal dominant optic atrophy
    La Morgia, C.
    Caporali, L.
    Tagliavini, F.
    Palombo, F.
    Amore, G.
    Carbonelli, M.
    Barboni, P.
    Liguori, R.
    Carelli, V.
    EUROPEAN JOURNAL OF NEUROLOGY, 2020, 27 : 71 - 71
  • [37] OPA1 mutations in dominant optic atrophy: domain-specific defects in mitochondrial fusion and apoptotic regulation
    Kexuan Zhang
    Wenqing Zhang
    Lin Zhang
    Xiaorong Hou
    Runyi Tian
    Zhengmao Hu
    Lili Yin
    Zhonghua Hu
    Journal of Translational Medicine, 23 (1)
  • [38] OPA1 Mutations Associated with Dominant Optic Atrophy Influence Optic Nerve Head Size
    Barboni, Piero
    Carbonelli, Michele
    Savini, Giacomo
    Foscarini, Beatrice
    Parisi, Vincenzo
    Valentino, Maria L.
    Carta, Arturo
    De Negri, Annamaria
    Sadun, Federico
    Zeviani, Massimo
    Sadun, Alfredo A.
    Schimpf, Simone
    Wissinger, Bernd
    Carelli, Valerio
    OPHTHALMOLOGY, 2010, 117 (08) : 1547 - 1553
  • [39] Autosomal dominant optic atrophy: A novel treatment for OPA1 splice defects using U1 snRNA adaption
    Jueschke, Christoph
    Klopstock, Thomas
    Catarino, Claudia B.
    Owczarek-Lipska, Marta
    Wissinger, Bernd
    Neidhardt, John
    MOLECULAR THERAPY-NUCLEIC ACIDS, 2021, 26 : 1186 - 1197
  • [40] OPA1 (Kjer type) dominant optic atrophy: A novel mitochondrial disease
    Delettre, C
    Lenaers, G
    Pelloquin, L
    Belenguer, P
    Hamel, CP
    MOLECULAR GENETICS AND METABOLISM, 2002, 75 (02) : 97 - 107
12345