Clinical outcomes of ischemic stroke patients after thrombolytic therapy

被引：3

作者：

do Nascimento, Kleiton Goncalves ^{[1
]}

Ribeiro Chavaglia, Suzel Regina ^{[1
]}

Pires, Patricia da Silva ^{[2
]}

Felix Ribeiro, Sonia Beatriz ^{[1
]}

Barbosa, Maria Helena ^{[1
]}

机构：

[1] Univ Fed Triangulo Mineiro, Uberaba, MG, Brazil

[2] Univ Fed Bahia, Vitoria Da Conquista, BA, Brazil

来源：

ACTA PAULISTA DE ENFERMAGEM | 2016年 / 29卷 / 06期

关键词：

Stroke; Thrombolytic therapy; Tissue plasminogen activator; TISSUE-PLASMINOGEN ACTIVATOR; SYMPTOMATIC INTRACRANIAL HEMORRHAGE; SAFE IMPLEMENTATION; REGISTRY; MULTICENTER; PREDICTORS; CARE; GUIDELINES; MANAGEMENT; BRAZIL;

D O I：

10.1590/1982-0194201600091

中图分类号：

R47 [护理学];

学科分类号：

1011 ;

摘要：

Objective: To analyze outcomes and associated factors in ischemic stroke patients submitted to thrombolytic therapy. Methods: This was a retrospective cohort study of ischemic stroke patients submitted to thrombolytic therapy. Comorbidities, neurologic deficits and time of thrombolysis were described. The chi-squared test was used to assess association among comorbidities, time of thrombolysis, and occurrence of hemorrhagic transformation. Results: There was a high frequency of comorbidities. Mean neurological deficit score was 15 points. Mean time window was 98 minutes and needle-to-door time, 89.9 minutes. Hemorrhagic transformation was observed in 20 patients. Bivariate analysis revealed that hemorrhagic transformation was associated with greater neurologic deficit score, atrial fibrillation and heart disease. Neurologic deficit fell from 51% to 12.5% between admission and discharge. Conclusion: Thrombolytic therapy presented positive outcomes, regardless of long thrombolysis time and high neurologic deficit scores.

引用

页码：650 / 657

页数：8

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