Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas

被引：188

作者：

Ordóñez, NG ^{[1
]}

机构：

[1] Univ Texas, MD Anderson Canc Ctr, Houston, TX 77030 USA

来源：

ADVANCES IN ANATOMIC PATHOLOGY | 2000年 / 7卷 / 02期

关键词：

transcription factors; TTF-1; lung neoplasms; thyroid neoplasms; immunohistochemistry;

D O I：

10.1097/00125480-200007020-00007

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Thyroid transcription factor-1 (TTF-1) is a tissue specific transcription Factor expressed in epithelial cells of the thyroid and lung, as well as in certain areas of the brain. Recent investigations have shown that TTF-1 is also commonly present in a wide variety of thyroid and lung tumors. Because of its restrictive expression, TTF-1 is a useful immunohistochemical marker in the diagnosis of tumors of thyroid or lung origin.

引用

页码：123 / 127

页数：5

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