Pagetoid spread to oral mucosa from submandibular gland salivary duct carcinoma: a case report

被引：4

作者：

Kikuchi, Yoshinao ^{[1
]}

Uozaki, Hiroshi ^{[1
]}

Itoyama, Shinji ^{[2
]}

Saijo, Hideto ^{[3
]}

Takato, Tsuyoshi ^{[3
]}

Fukayama, Masashi ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Med, Dept Pathol, Tokyo 1130033, Japan

[2] Saitama Med Univ, Saitama Med Ctr, Dept Pathol, Saitama 3508550, Japan

[3] Tokyo Univ Hosp, Dept Oral & Maxillofacial Surg Dent & Orthodont, Tokyo 1130033, Japan

来源：

HUMAN PATHOLOGY | 2009年 / 40卷 / 07期

关键词：

Pagetoid spread; Salivary duct carcinoma; Oral mucosa; Salivary gland; Submandibular gland; DISEASE;

D O I：

10.1016/j.humpath.2008.11.016

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Salivary duct carcinoma is a high-grade malignant tumor arising predominantly in the major salivary glands. We describe herein a rare presentation of salivary duct carcinoma arising in the submandibular gland and showing pagetoid spread to the oral mucosa. A 46-year-old man was admitted with a 2-year history of swelling in the floor of the mouth. Resection of the submandibular gland tumor was followed by mucosal biopsy around the aperture of the right Wharton's duct. The tumor recurred in the oral mucosa with pagetoid spread and extended widely in the oral cavity for the following 10 years, despite chemo- and radiotherapy. Mucosal spread, although a relatively remote possibility, can occur in the setting of salivary duct carcinoma. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：1036 / 1039

页数：4

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