Brown Fat in Humans: Turning up the Heat on Obesity

被引：133

作者：

Seale, Patrick ^{[1
,2
]}

Lazar, Mitchell A. ^{[3
,4
]}

机构：

[1] Harvard Univ, Sch Med, Dana Farber Canc Inst, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA

[3] Univ Penn, Dept Med, Div Endocrinol Diabet & Metab, Philadelphia, PA 19104 USA

[4] Inst Diabet Obes & Metab, Philadelphia, PA USA

来源：

DIABETES | 2009年 / 58卷 / 07期

关键词：

ADIPOSE-TISSUE; TRANSCRIPTIONAL CONTROL; ADULT HUMANS; THERMOGENESIS; PRDM16; MUSCLE; MICE; MEN;

D O I：

10.2337/db09-0622

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1482 / 1484

页数：3

共 17 条

[1] CONTRIBUTION OF BAT AND SKELETAL-MUSCLE TO THERMOGENESIS INDUCED BY EPHEDRINE IN MAN [J].

ASTRUP, A ;

BULOW, J ;

MADSEN, J ;

CHRISTENSEN, NJ .

AMERICAN JOURNAL OF PHYSIOLOGY, 1985, 248 (05) :E507-E515

[2] THE RESPONSE TO LONG-TERM OVERFEEDING IN IDENTICAL-TWINS [J].

BOUCHARD, C ;

TREMBLAY, A ;

DESPRES, JP ;

NADEAU, A ;

LUPIEN, PJ ;

THERIAULT, G ;

DUSSAULT, J ;

MOORJANI, S ;

PINAULT, S ;

FOURNIER, G .

NEW ENGLAND JOURNAL OF MEDICINE, 1990, 322 (21) :1477-1482

[3] Epidemiology, trends, and morbidities of obesity and the metabolic syndrome [J].

Bray, GA ;

Bellanger, T .

ENDOCRINE, 2006, 29 (01) :109-117

[4] Brown adipose tissue: Function and physiological significance [J].

Cannon, B ;

Nedergaard, J .

PHYSIOLOGICAL REVIEWS, 2004, 84 (01) :277-359

[5] THE CHARACTERIZATION AND ENERGETIC POTENTIAL OF BROWN ADIPOSE-TISSUE IN MAN [J].

CUNNINGHAM, S ;

LESLIE, P ;

HOPWOOD, D ;

ILLINGWORTH, P ;

JUNG, RT ;

NICHOLLS, DG ;

PEDEN, N ;

RAFAEL, J ;

RIAL, E .

CLINICAL SCIENCE, 1985, 69 (03) :343-348

[6] Identification and Importance of Brown Adipose Tissue in Adult Humans. [J].

Cypess, Aaron M. ;

Lehman, Sanaz ;

Williams, Gethin ;

Tal, Ilan ;

Rodman, Dean ;

Goldfine, Allison B. ;

Kuo, Frank C. ;

Palmer, Edwin L. ;

Tseng, Yu-Hua ;

Doria, Alessandro ;

Kolodny, Gerald M. ;

Kahn, C. Ronald .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (15) :1509-1517

[7] Molecular physiology of weight regulation in mice and humans [J].

Leibel, R. L. .

INTERNATIONAL JOURNAL OF OBESITY, 2008, 32 (Suppl 7) :S98-S108

[8]

Lichtenbelt WDV, 2009, NEW ENGL J MED, V360, P1500, DOI 10.1056/NEJMoa0808718

[9] Unexpected evidence for active brown adipose tissue in adult humans [J].

Nedergaard, Jan ;

Bengtsson, Tore ;

Cannon, Barbara .

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2007, 293 (02) :E444-E452

[10]

ROTHWELL NJ, 1983, ADV NUTR RES, V5, P201

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