ASSESSMENT OF MULTIPLE HORMONAL ACTIVITIES IN WASTEWATER AT DIFFERENT STAGES OF TREATMENT

被引:69
作者
Bain, Peter A. [1 ]
Williams, Mike [1 ]
Kumar, Anu [1 ]
机构
[1] Commonwealth Sci & Ind Res Org Land & Water, Glen Osmond, SA, Australia
关键词
Endocrine-disrupting compounds; Effects-based monitoring; Emerging pollutants; In vitro bioassays; SEWAGE-TREATMENT PLANTS; ENDOCRINE DISRUPTING CHEMICALS; IN-VITRO; ESTROGENIC ACTIVITY; MUNICIPAL SEWAGE; ORGANOTIN COMPOUNDS; STEROID-HORMONES; RECEPTOR AGONIST; SURFACE-WATER; CALUX METHOD;
D O I
10.1002/etc.2676
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Changes in the endocrine potency of municipal wastewater at 3 wastewater treatment plants (WWTPs) in Australia were investigated using a panel of in vitro receptor-driven transactivation assays. The assays were based on human estrogen receptor , androgen receptor, progesterone receptor, glucocorticoid receptor, and peroxisome proliferator-activated receptor 2. Total removal efficiencies for estrogenic activity in the dissolved phase were 79.8% to 99.4%. Chemical analysis of 17-estradiol, estrone, and 17-ethinylestradiol levels showed that they accounted for the majority of the observed in vitro estrogenic activity in the final effluents but only 18% to 70% of estrogenic activity in the influents. Removal efficiency for androgenic activity was 97.5% to 100%. Endocrine activity levels were low in the final effluent of the WWTP with the lowest catchment population, with only estrogenic activity detected. In the final effluent of the WWTP with an intermediate catchment population, estrogenic, glucocorticoid, and peroxisome proliferator activities were detected. Estrogenic, antiandrogenic, progestagenic, glucocorticoid, and peroxisome proliferator activities were detected in the final effluent of the WWTP with the highest catchment population. The present study confirms the efficacy of secondary and tertiary treatment in reducing the concentrations of endocrine-active compounds in municipal wastewater. Further work is required to determine the possible health risks to aquatic biota posed by multiple hormonal activities present at low levels. Environ Toxicol Chem 2014;33:2297-2307. (c) 2014 SETAC
引用
收藏
页码:2297 / 2307
页数:11
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