Micellar Catalysis for Ruthenium(II)-Catalyzed C-H Arylation: Weak-Coordination-Enabled C-H Activation in H2O

被引：49

作者：

Yetra, Santhivardhana Reddy ^{[1
]}

Rogge, Torben ^{[1
]}

Warratz, Svenja ^{[1
]}

Struwe, Julia ^{[1
]}

Peng, Wentao ^{[2
]}

Vana, Philipp ^{[2
]}

Ackermann, Lutz ^{[1
]}

机构：

[1] Georg August Univ Gottingen, Inst Organ & Biomol Chem, Tammannstr 2, D-37077 Gottingen, Germany

[2] Georg August Univ Gottingen, Inst Phys Chem, Tammannstr 2, D-37077 Gottingen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2019年 / 58卷 / 22期

关键词：

arylation; C-H activation; micellar catalysis; ruthenium; thioketones; SUZUKI-MIYAURA COUPLINGS; PLANAR CHIRAL FERROCENES; CROSS-COUPLINGS; BOND ACTIVATION; ROOM-TEMPERATURE; ASYMMETRIC CATALYSIS; WATER; ARYL; PALLADIUM; FUNCTIONALIZATION;

D O I：

10.1002/anie.201901856

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chemoselective C-H arylations were accomplished through micellar catalysis by a versatile single-component ruthenium catalyst. The strategy provided expedient access to C-H-arylated ferrocenes with wide functional-group tolerance and ample scope through weak chelation assistance. The sustainability of the C-H arylation was demonstrated by outstanding atom-economy and recycling studies. Detailed computational studies provided support for a facile C-H activation through thioketone assistance.

引用

页码：7490 / 7494

页数：5

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