Successful erythropoietin treatment for severe anemia in nephrotic syndrome without renal dysfunction

被引:14
作者
Ishimitsu, T [1 ]
Ono, H [1 ]
Sugiyama, M [1 ]
Asakawa, H [1 ]
Oka, K [1 ]
Numabe, A [1 ]
Abe, M [1 ]
Matsuoka, H [1 ]
Yagi, S [1 ]
机构
[1] DOKKYO UNIV, SCH MED, DEPT MED, DIV HYPERTENS & CARDIORENAL DIS, MIBU, TOCHIGI 32102, JAPAN
关键词
nephrotic syndrome; anemia; erythropoietin;
D O I
10.1159/000189460
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
A 62-year-old woman presented with nephrotic syndrome and severe anemia although the renal function was not impaired. Renal biopsy revealed the histology of membranoproliferative glomerulonephritis, and the proteinuria was resistant to steroid therapy. Iron deficiency, bleeding and other causes of anemia were ruled out, however, her serum erythropoietin level was inappropriately low. The anemia was rapidly corrected by administration of recombinant human erythropoietin. It is suggested that inappropriately low erythropoietin level, in part at least, accounts for the anemia in nephrotic Syndrome. It is proposed that erythropoietin therapy should be taken into consideration for severe anemia in nephrotic syndrome even when the renal function is not impaired.
引用
收藏
页码:607 / 610
页数:4
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