Nanotechnology-based Polymeric Bio(muco)Adhesive Platforms for Controlling Drug Delivery - properties, Methodologies and Applications

被引：31
作者：
Carvalho, Flavia Chiva [1 ]
Chorilli, Marius [1 ]
Daflon Gremiao, Maria Palmira [1 ]
机构：
[1] Univ Estadual Paulista, Fac Ciencias Farmaceut Araraquara, Dept Farmacos & Medicamentos, Sao Paulo, Brazil
来源：
POLIMEROS-CIENCIA E TECNOLOGIA | 2014年 / 24卷 / 02期
关键词：
Bio(muco)adhesion; bioadhesion; drug delivery systems; nanotechnology; Bio(muco)bioadhesion mechanisms; Bio(muco)bioadhesion measurements; IN-VITRO; MUCOADHESIVE PROPERTIES; PERIODONTAL-DISEASE; SYSTEMS; NANOPARTICLES; PROPOLIS; CHITOSAN; DESIGN; MICROPARTICLES; FORMULATION;
D O I：
10.4322/polimeros.2014.043
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Studies using bio(muco)adhesive drug delivery systems have recently gained great interest, which can promote drug targeting and more specific contact of the drug delivery system with the various absorptive membranes of the body. This technological platform associated with nanotechnology offers potential for controlling drug delivery; therefore, they are excellent strategies to increase the bioavailability of drugs. The objective of this work was to study nanotechnology-based polymeric bio(muco)adhesive platforms for controlling drug delivery, highlighting their properties, how the bio(muco)adhesion can be measured and their potential applications for different routes of administration.
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页码：203 / 213
页数：11
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