High performance liquid chromatographic determination of phenoxetol, methyl paraben, ethyl paraben, n-propyl paraben, iso-butyl paraben, n-butyl paraben and croconazole center dot HCl

A high performance liquid chromatographic technique has been used to determine phenoxetol, methyl paraben, ethyl paraben, n-propyl paraben, iso-butyl paraben, n-butyl paraben and croconazole . HCl. The method developed involves isocratic, reversed phase chromatography. The range of quantitation was found to be 90-135.0 mu g ml(-1) for phenoxetol, 2.0-30.0 mu g ml(-1) for methyl paraben, 0.5-7.5 mu g ml(-1) for ethyl paraben, 0.3-4.5 mu g ml(-1) for n-propyl paraben, 0.3-4.5 mu g ml(-1) for iso-butyl paraben, 0.5-7.5 mu g ml(-1) for n-butyl paraben and 20.0-300 mu g ml(-1) for croconazole . HCL. Linear regression analysis of the data demonstrates the adequate performance of the method in terms of precision and accuracy.