A dual pathway inhibition strategy using BKM120 combined with vemurafenib is poorly tolerated in BRAF V600E/K mutant advanced melanoma

被引:17
作者
Algazi, Alain Patrick [1 ]
Rotow, Julia [1 ]
Posch, Christian [2 ,3 ]
Ortiz-Urda, Susana [4 ]
Algazi, Alain Patrick [1 ]
Munster, Pamela N. [1 ]
Daud, Adil [1 ]
机构
[1] UCSF Hematol & Oncol, San Francisco, CA USA
[2] Tech Univ Munich, Dept Dermatol & Allergy, Munich, Germany
[3] Sigmund Freud Univ, Sch Med, Vienna, Austria
[4] UCSF Dermatol, San Francisco, CA USA
关键词
DOSE-ESCALATION; PHASE-I; TRAMETINIB; PI3K; PTEN; NRAS;
D O I
10.1111/pcmr.12777
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:603 / 606
页数:4
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