The preprophase band of microtubules controls the robustness of division orientation in plants

被引：124

作者：

Schaefer, Estelle ^{[1
,3
]}

Belcram, Katia ^{[1
]}

Uyttewaal, Magalie ^{[1
]}

Duroc, Yann ^{[1
]}

Goussot, Magali ^{[1
]}

Legland, David ^{[1
,4
]}

Laruelle, Elise ^{[1
,2
]}

de Tauzia-Moreau, Marie-Ludivine ^{[1
]}

Pastuglia, Martine ^{[1
]}

Bouchez, David ^{[1
]}

机构：

[1] Univ Paris Saclay, CNRS, Inst Jean Pierre Bourgin, INRA,AgroParisTech, F-78000 Versailles, France

[2] Univ Paris Saclay, Math & Informat Appl Genome Environm, INRA, F-78350 Jouy En Josas, France

[3] Lawrence Berkeley Natl Lab, Joint Bioenergy Inst, Berkeley, CA USA

[4] INRA, Biopolymeres Interact Assemblages UR1268, Nantes, France

来源：

SCIENCE | 2017年 / 356卷 / 6334期

关键词：

CELL-DIVISION; MITOTIC SPINDLE; PROTEINS; GENE; CYTOSKELETON; PATTERNS; ARRAYS; COMMON;

D O I：

10.1126/science.aal3016

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Controlling cell division plane orientation is essential for morphogenesis in multicellular organisms. In plant cells, the future cortical division plane is marked before mitotic entry by the preprophase band (PPB). Here, we characterized an Arabidopsis trm (TON1 Recruiting Motif) mutant that impairs PPB formation but does not affect interphase microtubules. Unexpectedly, PPB disruption neither abolished the capacity of root cells to define a cortical division zone nor induced aberrant cell division patterns but rather caused a loss of precision in cell division orientation. Our results advocate for a reassessment of PPB function and division plane determination in plants and show that a main output of this microtubule array is to limit spindle rotations in order to increase the robustness of cell division.

引用

页码：186 / 189

页数：4

共 16 条

[1] Mitotic Spindle Organization by the Preprophase Band [J].