Annual Incidence of Adult and Pediatric In-Hospital Cardiac Arrest in the United States

被引:318
作者
Holmberg, Mathias J. [1 ,2 ]
Ross, Catherine E. [4 ]
Fitzmaurice, Garrett M. [5 ,6 ,7 ]
Chan, Paul S. [8 ]
Duval-Arnould, Jordan [9 ]
Grossestreuer, Anne V. [2 ]
Yankama, Tuyen [2 ]
Donnino, Michael W. [2 ,3 ]
Andersen, Lars W. [1 ,2 ]
Moskowitz, Ari
Edelson, Dana
Ornato, Joseph
Berg, Katherine
Peberdy, Mary Ann
Churpek, Matthew
Kurz, Michael
Starks, Monique Anderson
Girotra, Saket
Perman, Sarah
Goldberger, Zachary
Duval-Arnould, Jordan [9 ]
Atkins, Dianne
Foglia, Elizabeth
Fink, Ericka
Lasa, Javier J.
Roberts, Joan
Bembea, Melanie
Gaies, Michael
Kleinman, Monica
Gupta, Punkaj
Sutton, Robert
Sawyer, Taylor
机构
[1] Aarhus Univ Hosp, Dept Clin Med, Res Ctr Emergency Med, Aarhus, Denmark
[2] Beth Israel Deaconess Med Ctr, Dept Emergency Med, Ctr Resuscitat Sci, Boston, MA 02215 USA
[3] Beth Israel Deaconess Med Ctr, Dept Internal Med, Div Pulm Crit Care & Sleep Med, Boston, MA 02215 USA
[4] Harvard Med Sch, Boston Childrens Hosp, Dept Med, Div Med Crit Care, Boston, MA 02115 USA
[5] Harvard Med Sch, Dept Psychiat, Boston, MA 02115 USA
[6] Harvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA USA
[7] McLean Hosp, Lab Psychiat Biostat, 115 Mill St, Belmont, MA 02178 USA
[8] Univ Missouri, St Lukes Mid Amer Heart Inst, Kansas City, MO 64110 USA
[9] Johns Hopkins Univ, Sch Med, Dept Anesthesiol & Crit Care Med, Div Hlth Sci Informat, Baltimore, MD 21205 USA
来源
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES | 2019年 / 12卷 / 07期
关键词
epidemiology; heart arrest; hospitals; incidence; CARDIOPULMONARY-RESUSCITATION; GUIDELINES;
D O I
10.1161/CIRCOUTCOMES.119.005580
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Previous incidence estimates may no longer reflect the current public health burden of cardiac arrest in hospitalized adult and pediatric patients across the United States. The aim of this study was to estimate the contemporary annual incidence of in-hospital cardiac arrest in adults and children across the United States and to describe trends in incidence between 2008 and 2017. Methods and Results: Using the Get With The Guidelines-Resuscitation registry, we developed a negative binomial regression model to estimate the incidence of index pulseless in-hospital cardiac arrest based on hospital-level characteristics. The model was used to predict the number of in-hospital cardiac arrests in all US hospitals, using data from the American Hospital Association Annual Survey. We performed separate analyses for adult (>= 18 years) and pediatric (<18 years) cardiac arrests. Additional analyses were performed for recurrent cardiac arrests and pediatric patients requiring cardiopulmonary resuscitation for poor perfusion (nonpulseless events). The average annual incidence of in-hospital cardiac arrest in the United States was estimated at 292 000 (95% prediction interval, 217 600-503 500) adult and 15 200 pediatric cases, of which 7100 (95% prediction interval, 4400-9900) cases were pulseless cardiac arrests and 8100 (95% prediction interval, 4700-11 500) cases were nonpulseless events. The rate of adult cardiac arrests increased over time, while pediatric events remained more stable. When including both index and recurrent in-hospital cardiac arrests, the average annual incidence was estimated at 357 900 (95% prediction interval, 247 100-598 400) adult and 19 900 pediatric cases, of which 8300 (95% prediction interval, 4900-11 200) cases were pulseless cardiac arrests and 11 600 (95% prediction interval, 6400-16 700) cases were nonpulseless events. Conclusions: There are approximate to 292 000 adult in-hospital cardiac arrests and 15 200 pediatric in-hospital events in the United States each year. This study provides contemporary estimates of the public health burden of cardiac arrest among hospitalized patients.
引用
收藏
页数:8
相关论文
共 18 条
[1]  
Agency for Healthcare Research and Quality,, HCUP FAST STATS HEAL
[2]  
American Hospital Association (AHA), AHA EST PROC
[3]  
American Hospital Association (AHA), AHA ANN SURV DAT FIS
[4]  
American Hospital Association (AHA), AHA REG REQ HOSP
[5]  
Benjamin EJ, 2017, CIRCULATION, V135, pE146, DOI [10.1161/CIR.0000000000000485, 10.1161/CIR.0000000000000558, 10.1161/CIR.0000000000000530]
[6]   Rapid Response Teams A Systematic Review and Meta-analysis [J].
Chan, Paul S. ;
Jain, Renuka ;
Nallmothu, Brahmajee K. ;
Berg, Robert A. ;
Sasson, Comilla .
ARCHIVES OF INTERNAL MEDICINE, 2010, 170 (01) :18-26
[7]  
de Caen AR, 2015, CIRCULATION, V132, pS177, DOI [10.1161/CIR.0000000000000266, 10.1161/CIR.0000000000000275]
[8]   Cardiopulmonary Resuscitation for Bradycardia With Poor Perfusion Versus Pulseless Cardiac Arrest [J].
Donoghue, Aaron ;
Berg, Robert A. ;
Hazinski, Mary Fran ;
Praestgaard, Amy H. ;
Roberts, Kathryn ;
Nadkarni, Vinay M. .
PEDIATRICS, 2009, 124 (06) :1541-1548
[9]   Administrative Codes for Capturing In-Hospital Cardiac Arrest [J].
Khera, Rohan ;
Spertus, John A. ;
Starks, Monique A. ;
Tang, Yuanyuan ;
Bradley, Steven M. ;
Girotra, Saket ;
Chan, Paul S. .
JAMA CARDIOLOGY, 2017, 2 (11) :1275-1277
[10]   Prevalence and outcomes of pediatric in-hospital cardiopulmonary resuscitation in the United States: An analysis of the Kids' Inpatient Database [J].
Knudson, Jarrod D. ;
Neish, Steven R. ;
Cabrera, Antonio G. ;
Lowry, Adam W. ;
Shamszad, Pirouz ;
Morales, David L. S. ;
Graves, Daniel E. ;
Williams, Eric A. ;
Rossano, Joseph W. .
CRITICAL CARE MEDICINE, 2012, 40 (11) :2940-2944