Space-time cluster analysis of invasive Meningococcal disease

被引：13
作者：
Hoebe, CJPA
de Melker, H
Spanjaard, L
Dankert, J
Nagelkerke, N
机构：
[1] Eastern S Limburg Municipal Publ Hlth Serv, Dept Infect Dis, NL-6400 AD Heerlen, Netherlands
[2] Natl Inst Publ Hlth & Environm, NL-3720 BA Bilthoven, Netherlands
[3] Netherlands Reference Lab Bacterial Meningitis, Amsterdam, Netherlands
来源：
EMERGING INFECTIOUS DISEASES | 2004年 / 10卷 / 09期
关键词：
D O I：
10.3201/eid1009.030992
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Clusters are recognized when meningococcal cases of the same phenotypic strain (markers: serogroup, serotype, and subtype) occur in spatial and temporal proximity. The incidence of such clusters was compared to the incidence that would be expected by chance by using space-time nearest-neighbor analysis of 4,887 confirmed invasive meningococcal cases identified in the 9-year surveillance period 1993-2001 in the Netherlands. Clustering beyond chance only occurred among the closest neighboring cases (comparable to secondary cases) and was small (3.1%, 95% confidence interval 2.1%-4.1%).
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收藏
页码：1621 / 1626
页数：6
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